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ChemicalBook >> CAS DataBase List >>N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide

N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide

CAS No.
1338247-35-0
Chemical Name:
N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide
Synonyms
LIMKI-3;CS-2190;BMS 5;BMS5;BMS-5 ≥95%;BMS-5， LIMKI-3;LIMKI-3;BMS5;BMS 5;LIMKI3;LIMKI 3;LIMKi3,inhibit,LIM Kinase (LIMK),LIMKs,Inhibitor,BMS 5,BMS-5,LIMKi-3;N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide;N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyramide[BMS5;N-[5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-2-methylpropanamide
CBNumber:
CB72598623
Molecular Formula:
C17H14Cl2F2N4OS
Molecular Weight:
431.29
MDL Number:
MFCD17019327
MOL File:
1338247-35-0.mol
Last updated:2024-10-25 23:13:37

N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide Properties

Density 1.54±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO:PBS (pH 7.2) (1:5):0.2(Max Conc. mg/mL);0.46(Max Conc. mM)
Ethanol:3.0(Max Conc. mg/mL);6.96(Max Conc. mM)
pka 9.51±0.50(Predicted)
form White powder.
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P280

N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 435930 LIM Kinase Inhibitor I, LIMKi 3 - Calbiochem The LIM Kinase Inhibitor I, LIMKi 3 controls the biological activity of LIM Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. 1338247-35-0 10MG $259 2022-05-15 Buy
Cayman Chemical 21072 BMS-5 ≥98% 1338247-35-0 1mg $48 2024-03-01 Buy
Cayman Chemical 21072 BMS-5 ≥98% 1338247-35-0 5mg $152 2024-03-01 Buy
Cayman Chemical 21072 BMS-5 ≥98% 1338247-35-0 10mg $232 2024-03-01 Buy
Tocris 4745 LIMKi3 ≥98%(HPLC) 1338247-35-0 10 $227 2021-12-16 Buy
Product number Packaging Price Buy
435930 10MG $259 Buy
21072 1mg $48 Buy
21072 5mg $152 Buy
21072 10mg $232 Buy
4745 10 $227 Buy

N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide Chemical Properties,Uses,Production

Uses

LIMKi 3 is a LIM kinase 1 (LIMK1) inhibitor that has antitumor properties.

Definition

ChEBI: LimKi 3 is a member of the class of pyrazoles that is 1-(2,6-dichlorophenyl)-1H-pyrazole which is substituted by a difluoromethyl group at position 3 and by a 2-(isobutyrylamino)-1,3-thiazol-5-yl group at position 5. It is a a potent cell-permeable inhibitor of LIM kinase 1 and 2. It has a role as a LIM kinase inhibitor. It is a member of pyrazoles, a member of 1,3-thiazoles, a dichlorobenzene, an organofluorine compound and a secondary carboxamide.

storage

Store at +4°C

N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 72)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32820 60
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29815 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32002 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38460 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43340 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58

View Lastest Price from N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BMS-5 pictures 2024-10-25 BMS-5
1338247-35-0
 US $46.00-125.00 / mg 99.88% 10g TargetMol Chemicals Inc.
Mitoquinone mesylateN-{5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]- 1,3-thiazol-2-yl}-2-methylpropanamide pictures 2020-01-02 Mitoquinone mesylateN-{5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]- 1,3-thiazol-2-yl}-2-methylpropanamide
1338247-35-0
 US $1.00 / KG 1KG Min98% HPLC g/kg/ton Career Henan Chemical Co
  • BMS-5 pictures
  • BMS-5
    1338247-35-0
  • US $46.00-125.00 / mg
  • 99.88%
  • TargetMol Chemicals Inc.
N-(5-(1-(2,6-dichlorophenyl)-3-(difluoroMethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyraMide LIMKI-3 Mitoquinone mesylateN-{5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]- 1,3-thiazol-2-yl}-2-methylpropanamide BMS-5， LIMKI-3 CS-2190 BMS-5 ≥95% BMS 5;BMS5 N-{5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]- 1,3-thiazol-2-yl}-2-methylpropanamide N-[5-[1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-2-methylpropanamide LIMKI-3;BMS5;BMS 5;LIMKI3;LIMKI 3 Propanamide, N-[5-[1-(2,6-dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl]-2-thiazolyl]-2-methyl- N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2-yl)isobutyramide[BMS5 LIMKi3,inhibit,LIM Kinase (LIMK),LIMKs,Inhibitor,BMS 5,BMS-5,LIMKi-3 1338247-35-0 C17H14Cl2F2N4OS