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ChemicalBook >> CAS DataBase List >>1-(CHLOROACETYL)-L-PROLINE METHYL ESTER

1-(CHLOROACETYL)-L-PROLINE METHYL ESTER

CAS No.
38074-72-5
Chemical Name:
1-(CHLOROACETYL)-L-PROLINE METHYL ESTER
Synonyms
vildagliptin Impurity U;Vildagliptin Impurity 68;Vildagliptin Impurity 13;Vildagliptin Impurity 78;chloroacetyl L-proline methyl ester;Methyl (2-chloroacetyl)-L-prolinate;N-Chloroacetyl-L-proline Methyl Ester;1-(CHLOROACETYL)-L-PROLINE METHYL ESTER;L-Proline, 1-(2-chloroacetyl)-, methyl ester;Vildagliptin Impurity-78/Vildagliptin Impurity-I
CBNumber:
CB72466999
Molecular Formula:
C8H12ClNO3
Molecular Weight:
205.64
MDL Number:
MFCD11849807
MOL File:
38074-72-5.mol
Last updated:2023-07-14 17:28:16

1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Properties

Boiling point 316.2±37.0 °C(Predicted)
Density 1.285±0.06 g/cm3(Predicted)
pka -3.02±0.40(Predicted)

1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Chemical Properties,Uses,Production

Uses

N-Chloroacetyl-L-proline Methyl Ester is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.

2577-48-2
79-04-9
38074-72-5
Synthesis of 1-(CHLOROACETYL)-L-PROLINE METHYL ESTER from methyl L-prolinate and Chloroacetyl chloride

1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

1-(CHLOROACETYL)-L-PROLINE METHYL ESTER Suppliers

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1-(CHLOROACETYL)-L-PROLINE METHYL ESTER vildagliptin Impurity U Vildagliptin Impurity 13 Vildagliptin Impurity 10/Methyl (2S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylate chloroacetyl L-proline methyl ester Vildagliptin Impurity 78 L-Proline, 1-(2-chloroacetyl)-, methyl ester (S)-methyl 1-(2-chloroacetyl)pyrrolidine-2-carboxylate N-Chloroacetyl-L-proline Methyl Ester (2S,2'S)-1,1'-(2,2'-(((3R,5R,7R)-adamantan-1-yl)azanediyl)bis(acetyl))bis(pyrrolidine-2-carbonitrile) hydrochloride Vildagliptin Impurity 68 Vildagliptin Impurity-78/Vildagliptin Impurity-I Vildagliptin Impurity-IQ: What is Vildagliptin Impurity-I Q: What is the CAS Number of Vildagliptin Impurity-I Q: What are the applications of Vildagliptin Impurity-I Methyl (2-chloroacetyl)-L-prolinate (S)-methyl 1-(2-chloroacetyl)pyrrolidine-2-carboxylate? (Vildagliptin Impurity) 38074-72-5