Boron, [1-?(4-?amino-?6,?7-?dimethoxy-?2-?quinazolinyl)?-?4-?[3-?[5-?[(3,?5-?dimethyl-?2H-?pyrrol-?2-?ylidene-?κN)?methyl]?-?1H-?pyrrol-?2-?yl-?κN]?-?1-?oxopropyl]?piperazinato]?difluoro-?, (T-?4)?-
- CAS No.
- 175799-93-6
- Chemical Name:
- Boron, [1-?(4-?amino-?6,?7-?dimethoxy-?2-?quinazolinyl)?-?4-?[3-?[5-?[(3,?5-?dimethyl-?2H-?pyrrol-?2-?ylidene-?κN)?methyl]?-?1H-?pyrrol-?2-?yl-?κN]?-?1-?oxopropyl]?piperazinato]?difluoro-?, (T-?4)?-
- Synonyms
- Boron, [1-?(4-?amino-?6,?7-?dimethoxy-?2-?quinazolinyl)?-?4-?[3-?[5-?[(3,?5-?dimethyl-?2H-?pyrrol-?2-?ylidene-?κN)?methyl]?-?1H-?pyrrol-?2-?yl-?κN]?-?1-?oxopropyl]?piperazinato]?difluoro-?, (T-?4)?-
- CBNumber:
- CB712868455
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Boron, [1-?(4-?amino-?6,?7-?dimethoxy-?2-?quinazolinyl)?-?4-?[3-?[5-?[(3,?5-?dimethyl-?2H-?pyrrol-?2-?ylidene-?κN)?methyl]?-?1H-?pyrrol-?2-?yl-?κN]?-?1-?oxopropyl]?piperazinato]?difluoro-?, (T-?4)?- Chemical Properties,Uses,Production
Uses
BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist with Ki values of 14.5, 43.3 nM for α1a-AR and α1b-AR, respectively. BODIPY FL prazosin also is a fluorescent ligand with the excitation and emission wavelengths are 485 and 535 nm, respectively. BODIPY FL prazosin can be used for study the differences in the subcellular localization of α1-adrenoceptor subtypes[1][2][3].
IC 50
α1A-adrenergic receptor: 14.5 nM (Ki); α1B-adrenergic receptor: 43.3 nM (Ki)
References
[1] Sugawara T, et al. Differences in the subcellular localization of alpha1-adrenoceptor subtypes can affect the subtype selectivity of drugs in a study with the fluorescent ligand BODIPY FL-prazosin. Life Sci. 2002 Mar 22;70(18):2113-24. DOI:10.1016/s0024-3205(01)01533-8
[2] Cerveny L, et al. Lack of interactions between breast cancer resistance protein (bcrp/abcg2) and selected antiepileptic agents. Epilepsia. 2006 Mar;47(3):461-8. DOI:10.1111/j.1528-1167.2006.00453.x
[3] Fuchs R, et al. α1-adrenergic drugs exhibit affinity to a thapsigargin-sensitive binding site and interfere with the intracellular Ca2+ homeostasis in human erythroleukemia cells. Exp Cell Res. 2011 Dec 10;317(20):2969-80. DOI:10.1016/j.yexcr.2011.08.003
Boron, [1-?(4-?amino-?6,?7-?dimethoxy-?2-?quinazolinyl)?-?4-?[3-?[5-?[(3,?5-?dimethyl-?2H-?pyrrol-?2-?ylidene-?κN)?methyl]?-?1H-?pyrrol-?2-?yl-?κN]?-?1-?oxopropyl]?piperazinato]?difluoro-?, (T-?4)?- Preparation Products And Raw materials
Raw materials
Preparation Products
Boron, [1-?(4-?amino-?6,?7-?dimethoxy-?2-?quinazolinyl)?-?4-?[3-?[5-?[(3,?5-?dimethyl-?2H-?pyrrol-?2-?ylidene-?κN)?methyl]?-?1H-?pyrrol-?2-?yl-?κN]?-?1-?oxopropyl]?piperazinato]?difluoro-?, (T-?4)?- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32265 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4838 | 58 |
| Shanghai Annengjian Biomedical Technology Co., LTD | 021-68781987 13818305065 | sales@energybiopharma.com | China | 529 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| mahaloong | +86-028-81192082 +86-18180560816 | sales@mahaloong.com | China | 596 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19930 | 58 |
View Lastest Price from Boron, [1-?(4-?amino-?6,?7-?dimethoxy-?2-?quinazolinyl)?-?4-?[3-?[5-?[(3,?5-?dimethyl-?2H-?pyrrol-?2-?ylidene-?κN)?methyl]?-?1H-?pyrrol-?2-?yl-?κN]?-?1-?oxopropyl]?piperazinato]?difluoro-?, (T-?4)?- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2024-11-20 | BODIPY FL prazosin
175799-93-6
|
US $293.00-987.00 / mg | 98.49% | 10g | TargetMol Chemicals Inc. |
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- BODIPY FL prazosin
175799-93-6
- US $293.00-987.00 / mg
- 98.49%
- TargetMol Chemicals Inc.