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ChemicalBook >> CAS DataBase List >>Benzamide, N-cyclopropyl-4-methyl-3-[3-[[1-methyl-1-[2-[2-(methylamino)ethoxy]phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]-

Benzamide, N-cyclopropyl-4-methyl-3-[3-[[1-methyl-1-[2-[2-(methylamino)ethoxy]phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]-

CAS No.
1095003-80-7
Chemical Name:
Benzamide, N-cyclopropyl-4-methyl-3-[3-[[1-methyl-1-[2-[2-(methylamino)ethoxy]phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]-
Synonyms
p38α inhibitor 2;p38α inhibitor 2,p-38α inhibitor 2;Benzamide, N-cyclopropyl-4-methyl-3-[3-[[1-methyl-1-[2-[2-(methylamino)ethoxy]phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]-
CBNumber:
CB68383448
Molecular Formula:
C27H33N5O3
Molecular Weight:
475.58
MDL Number:
MOL File:
1095003-80-7.mol
Last updated:2024-10-28 23:16:16

Benzamide, N-cyclopropyl-4-methyl-3-[3-[[1-methyl-1-[2-[2-(methylamino)ethoxy]phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]- Properties

Density 1.23±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 250 mg/mL (525.67 mM; Need ultrasonic)
form Solid
pka 14.72±0.20(Predicted)
color Off-white to light yellow

Benzamide, N-cyclopropyl-4-methyl-3-[3-[[1-methyl-1-[2-[2-(methylamino)ethoxy]phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0133424 p38αinhibitor2 98.97% 1095003-80-7 5mg $350 2021-12-16 Buy
ChemScene CS-0133424 p38αinhibitor2 98.97% 1095003-80-7 10mg $580 2021-12-16 Buy
ChemScene CS-0133424 p38αinhibitor2 98.97% 1095003-80-7 25mg $1100 2021-12-16 Buy
ChemScene CS-0133424 p38αinhibitor2 98.97% 1095003-80-7 50mg $1700 2021-12-16 Buy
ChemScene CS-0133424 p38αinhibitor2 98.97% 1095003-80-7 100mg $2500 2021-12-16 Buy
Product number Packaging Price Buy
CS-0133424 5mg $350 Buy
CS-0133424 10mg $580 Buy
CS-0133424 25mg $1100 Buy
CS-0133424 50mg $1700 Buy
CS-0133424 100mg $2500 Buy

Benzamide, N-cyclopropyl-4-methyl-3-[3-[[1-methyl-1-[2-[2-(methylamino)ethoxy]phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]- Chemical Properties,Uses,Production

Biological Activity

p38α inhibitor 2 is a highly potent and selective p38α MAPK inhibitor, with a pIC50 of 9.6. p38α inhibitor 2 inhibits the hERG ion channel (IC50=27 μM) and shows a promising selectivity profile when tested in a panel of 51 other protein kinases (<30% inhibition at 10 μM concentration) and a panel of 141 other biological targets[1].

References

[1]. Raubo P, et al. The discovery and evaluation of 3-amino-2(1H)-pyrazinones as a novel series of selective p38α MAP kinase inhibitors [published online ahead of print, 2020 Jul 15]. Bioorg Med Chem Lett. 2020;30(18):127412.

Benzamide, N-cyclopropyl-4-methyl-3-[3-[[1-methyl-1-[2-[2-(methylamino)ethoxy]phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, N-cyclopropyl-4-methyl-3-[3-[[1-methyl-1-[2-[2-(methylamino)ethoxy]phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		support@targetmol.com United States 38630 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 hanfangpharma@126.com China 29981 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19699 58

View Lastest Price from Benzamide, N-cyclopropyl-4-methyl-3-[3-[[1-methyl-1-[2-[2-(methylamino)ethoxy]phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
p38α inhibitor 2 pictures 2024-10-28 p38α inhibitor 2
1095003-80-7
 US $332.00-1410.00 / mg 10g TargetMol Chemicals Inc.
Benzamide, N-cyclopropyl-4-methyl-3-[3-[[1-methyl-1-[2-[2-(methylamino)ethoxy]phenyl]ethyl]amino]-2-oxo-1(2H)-pyrazinyl]- p38α inhibitor 2 p38α inhibitor 2,p-38α inhibitor 2 1095003-80-7