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ChemicalBook >> CAS DataBase List >>Benzamide, N-hydroxy-4-[[5-(2-thienyl)-1H-tetrazol-1-yl]methyl]-

Benzamide, N-hydroxy-4-[[5-(2-thienyl)-1H-tetrazol-1-yl]methyl]-

CAS No.
2247608-27-9
Chemical Name:
Benzamide, N-hydroxy-4-[[5-(2-thienyl)-1H-tetrazol-1-yl]methyl]-
Synonyms
ITF3756;Benzamide, N-hydroxy-4-[[5-(2-thienyl)-1H-tetrazol-1-yl]methyl]-
CBNumber:
CB68231596
Molecular Formula:
C13H11N5O2S
Molecular Weight:
301.32
MDL Number:
MOL File:
2247608-27-9.mol
Last updated:2025-04-30 13:36:08

Benzamide, N-hydroxy-4-[[5-(2-thienyl)-1H-tetrazol-1-yl]methyl]- Properties

Density 1.54±0.1 g/cm3(Predicted)
pka 8.74±0.10(Predicted)
form Solid
color Off-white to light yellow

Benzamide, N-hydroxy-4-[[5-(2-thienyl)-1H-tetrazol-1-yl]methyl]- Chemical Properties,Uses,Production

Uses

ITF 3756 is a potent and selective HDAC6 inhibitor. ITF 3756 reduces in vitro the expression of PD-L1 on human monocytes and on CD8 T cells, and shows anti-tumor activity[1].

References

[1] Gianluca Fossati, et al. Abstract 1358: The selective HDAC6 inhibitor ITF3756 stimulates an antitumor immune response and leads to tumor regression in combination with anti CTLA-4 antibody in a colon carcinoma murine model. Cancer Res (2022) 82 (12_Supplement): 1358.

Benzamide, N-hydroxy-4-[[5-(2-thienyl)-1H-tetrazol-1-yl]methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide, N-hydroxy-4-[[5-(2-thienyl)-1H-tetrazol-1-yl]methyl]- Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32268 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4472 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24856 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5528 58
Shanghai Easy CDMO Co.,Ltd 021-61734564 13854185395; info@easycdmo.com China 10030 58
Suzhou Haiben Pharmaceutical Co., Ltd 14760821013 13564957716 1816280386@qq.com China 8045 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd 025-58851090 17714375163 2881759498@qq.com China 13012 58
Sangon Biotech (Shanghai) Co.,Ltd. 400-821-026 Sales@sangon.com China 55710 58
Selleck Chemicals 400-668-6834 info@selleck.cn China 12071 58

View Lastest Price from Benzamide, N-hydroxy-4-[[5-(2-thienyl)-1H-tetrazol-1-yl]methyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ITF3756 pictures 2025-05-12 ITF3756
2247608-27-9
 US $38.00-143.00 / mg 97.31% 10g TargetMol Chemicals Inc.
  • ITF3756 pictures
  • ITF3756
    2247608-27-9
  • US $38.00-143.00 / mg
  • 97.31%
  • TargetMol Chemicals Inc.
Benzamide, N-hydroxy-4-[[5-(2-thienyl)-1H-tetrazol-1-yl]methyl]- ITF3756 2247608-27-9