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ChemicalBook >> CAS DataBase List >>Tilmicosin

Tilmicosin

CAS No.
108050-54-0
Chemical Name:
Tilmicosin
Synonyms
Timicosin;Tilmicosine;pulmotil;Dianthi Herba;EL 870;Micotil;Stmicco;LY 177370;Timicoxin;TILMICOSIN
CBNumber:
CB6463168
Molecular Formula:
C46H80N2O13
Molecular Weight:
869.15
MDL Number:
MFCD00864842
MOL File:
108050-54-0.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

Tilmicosin Properties

Melting point >97°C (dec.)
alpha D23 +12.75° (c = 0.010004 in CHCl3, 5 cm)
Boiling point 926.6±65.0 °C(Predicted)
Density 1.18±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Acetone (Slightly), DMSO (Slightly), Methanol (Sparingly)
pka pKa (66% DMF): 7.4, 8.5(at 25℃)
form Solid
color White to Off-White
InChIKey JTSDBFGMPLKDCD-XVFHVFLVSA-N
FDA 21 CFR 556.735; 558.618; 558.4
FDA UNII XL4103X2E3
EPA Substance Registry System Tilmicosin (108050-54-0)
UNSPSC Code 41116107

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
WGK Germany  3
HS Code  29419090
Hazardous Substances Data 108050-54-0(Hazardous Substances Data)

Tilmicosin price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 33864 Tilmicosin VETRANAL?, analytical standard, mix of isomers 108050-54-0 100mg $119 2024-03-01 Buy
Sigma-Aldrich 1667370 Tilmicosin United States Pharmacopeia (USP) Reference Standard 108050-54-0 250mg $436 2024-03-01 Buy
Usbiological 257406 Tilmicosin 108050-54-0 500mg $531 2021-12-16 Buy
TRC T440500 Tilmicosin,85% 108050-54-0 50mg $70 2021-12-16 Buy
AK Scientific A574 Tilmicosin,mixtureofisomers 108050-54-0 1g $312 2021-12-16 Buy
Product number Packaging Price Buy
33864 100mg $119 Buy
1667370 250mg $436 Buy
257406 500mg $531 Buy
T440500 50mg $70 Buy
A574 1g $312 Buy

Tilmicosin Chemical Properties,Uses,Production

Brief introduction

Tilmicosin is a relatively novel semi-synthetic macrolide antibiotics derived from tylosin for being applied to livestock and poultry. The chemical name is 4A-O-de (2, 6-dideoxy-methyl-3-C--L-ribose-pyran-hexyl)-20-deoxy-20-(3,5-dimethyl-1-piperidinyl)-[20 (cis: trans)] tylosin. Molecule formula is C46H80N2O13 and the molecular weight of 869.15.
Tilmicosin has a similar antibacterial spectrum as tylosin but has enhanced effect on the anti-Pasteurella multocida and hemolytic pasteurella. It was successfully developed in 1980s and initially used with a code of EL-870. Common trade names include Pulmotil ? Micotil ?, preparations include tilmicosin soluble powder, premix (20%) preparation, and injection. In 1990 it was approved in most European countries; it was approved in the US in 1992, and included in USP. China also has some domestic enterprises approved for production of tilmicosin.
Because of its special antibacterial activity and pharmacokinetic characteristics, the drug has been approved for clinical prevention and treatment of infectious diseases for cattle, goats, sheep, cows, pigs, and chickens. It is especially applied to the treatment of respiratory diseases of livestock, such as cattle Actinobacillus pleuropneumonia, Pasteurella disease, chicken mycoplasmosis and mastitis of lactating animals.
The above information is edited by the Chemicalbook of Dai Xiongfeng.

Chemical Properties

It is white or white powder with humidity: ≤5.0%.

Uses

It can be used as anti-bacterial.
It is mainly used for the treatment of infection caused by pleuropneumonia, Actinobacillus, Pasteurella and mycoplasma.

Chemical Properties

White Solid

Uses

Tilmicosin is a semi-synthetic antibiotic derived from desmycosin (tylosin B), a minor co-metabolite of tylosin. Tilmicosin is produced by reductive amination of desmycosin. Desmycosin itself is prepared by the partial hydrolysis of tylosin with the loss of the mycarosyl sugar. The piperidinyl group at C20 of tilmicosin provides a wider spectrum of antibiotic action, in particular good protection against Pasteurella in livestock.

Uses

A Macrolide antibiotic.

Uses

Macrolide antibiotic structurally related to tylosin. Antibacterial

Veterinary Drugs and Treatments

Tilmicosin is indicated for the treatment of bovine or ovine respiratory diseases (BRD) caused by Mannheimia (Pasturella) haemolytica.

Tilmicosin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 431)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Suikang Pharmaceutical Co.,Ltd.
+86-18239973690 +86-18239973690 sales@suikangpharm.com China 311 58
Hebei Chuanghai Biotechnology Co., Ltd 		+86-15531157085 +86-15531157085 abby@chuanghaibio.com China 8809 58
Hebei Mujin Biotechnology Co.,Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12816 58
shandong perfect biotechnology co.ltd 		+86-53169958659 +86-13153181156 sales@sdperfect.com China 294 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2472 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 10986 58
Nantong Guangyuan Chemicl Co,Ltd 		+undefined17712220823 admin@guyunchem.com China 615 58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		+8618092446649 sarah@tnjone.com China 1143 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD 		+8615350851019 admin@86-ss.com China 1001 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21631 55

View Lastest Price from Tilmicosin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tilmicosin pictures 2025-03-31 Tilmicosin
108050-54-0
 US $0.00 / kg 25kg ＞85% 10tons Henan Suikang Pharmaceutical Co.,Ltd.
Tilmicosin Premix pictures 2025-03-31 Tilmicosin Premix
108050-54-0
 US $1.00 / KG 1KG 99% 10mt Hebei Chuanghai Biotechnology Co., Ltd
Tilmicosin pictures 2025-03-29 Tilmicosin
108050-54-0
 US $0.00-0.00 / Kg/Drum 1KG 85% 500KG WUHAN FORTUNA CHEMICAL CO., LTD
  • Tilmicosin pictures
  • Tilmicosin
    108050-54-0
  • US $0.00 / kg
  • ＞85%
  • Henan Suikang Pharmaceutical Co.,Ltd.
  • Tilmicosin pictures
  • Tilmicosin
    108050-54-0
  • US $0.00-0.00 / Kg/Drum
  • 85%
  • WUHAN FORTUNA CHEMICAL CO., LTD

Tilmicosin Spectrum

4'-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-(3,5-dimethyl-1-piperidinyl)tyrosine [antibiotic] Tilmicosin,20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin Tilmicosin (250 mg) Herba Dianthi Superbi (11Z,13Z)-6-{[4-(diMethylaMino)-3,5-dihydroxy-6-Methyloxan-2-yl]oxy}-7-[2-(3,5-diMethylpiperidin-1-yl)ethyl]-16-ethyl-4-hydroxy-15-{[(5-hydroxy-3,4-diMethoxy-6-Methyloxan-2-yl)oxy]Methyl}-5,9,13-triMethyl-1-oxacyclohexadeca-11,13-diene-2,10-dione 20-Deoxy-20-(3,5-diMethylpiperidin-1-yl)-desMycosin, EL-870 Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]- 20%Tilmicosin Tilmicosin Base 20-DEOXO-20-(3,5-DIMETHYL-1-PIPERIDINYL)DESMYCOSIN Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-.alpha.-L-ribo-hexopyranosyl)-20-deoxo-20-(3R,5S)-3,5-dimethyl-1-piperidinyl- TILMICOSIN Tilmicosin, Vetranal 4A-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]tylosin Antibiotic EL 870 EL 870 LY 177370 Micotil Micotil 300 4A-O-De(2,6-dideoxy-3-C-methyl-a-L-ribo-hexopyranosyl)-20-deoxo-20-[(3R,5S)-3,5-dimethyl-1-piperidinyl]tylosin Stmicco Tilmicosin Solution, 1000ppm Tilmicosin CAS 108050-54-0 Tilmicosin,85% Qumai extract 6-[[4-(dimethylamino)-3,5-dihydroxy-6-methyl-2-oxanyl]oxy]-7-[2-(3,5-dimethyl-1-piperidinyl)ethyl]-16-ethyl-4-hydroxy-15-[(5-hydroxy-3,4-dimethoxy-6-methyl-2-oxanyl)oxymethyl]-5,9,13-trimethyl-1-oxacy Tilmicosin Standard(mixture of isomers) (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4S,5S,6R)-4-(Dimethylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-7-(2-((3R,5S)-3,5-dimethylpiperidin-1-yl)ethyl)-16-ethyl-4-hydroxy-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-5,9,13-trimethyloxacyclohexadeca-11,13-diene-2,10-dione Tilmicosin USP/EP/BP Dianthi extract TilmicosinQ: What is Tilmicosin Q: What is the CAS Number of Tilmicosin Q: What is the storage condition of Tilmicosin Q: What are the applications of Tilmicosin Tilmicosin (API) Tilmicosin (1667370) pulmotil Tilmicosine Dianthi Herba Timicosin Timicoxin Tilmicosin in methanol C17582000 Tilmicosin Tilmicosin 100 μg/ml Methanol Tilmicosin in Acetonitrile Timicoxin 108050-54-0 Tilmicosin, 10 mM in DMSO 108050-54-0 08050-54-0 C46H80N2O13 API Pharmaceutical intermediate Intermediates & Fine Chemicals Pharmaceuticals Chiral Reagents Active Pharmaceutical Ingredients