ZK756326(dihydrochloride)
- CAS No.
- 1780259-94-0
- Chemical Name:
- ZK756326(dihydrochloride)
- Synonyms
- ZK 756326 (hydrochloride);ZK756326(dihydrochloride);ZK 756326, non-peptide CCR8 chemokine receptor agonist
- CBNumber:
- CB63356182
- Molecular Formula:
- C21H29ClN2O3
- Molecular Weight:
- 392.92
- MDL Number:
- MFCD09038571
- MOL File:
- 1780259-94-0.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
ZK756326(dihydrochloride) price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28454 | ZK 756326 (hydrochloride) | 1780259-94-0 | 5mg | $101 | 2024-03-01 | Buy |
| Cayman Chemical | 28454 | ZK 756326 (hydrochloride) | 1780259-94-0 | 25mg | $399 | 2024-03-01 | Buy |
| Cayman Chemical | 28454 | ZK 756326 (hydrochloride) | 1780259-94-0 | 10mg | $182 | 2024-03-01 | Buy |
| ChemScene | CS-7558 | ZK756326dihydrochloride 98.28% | 1780259-94-0 | 25mg | $228 | 2021-12-16 | Buy |
| ChemScene | CS-7558 | ZK756326dihydrochloride 98.28% | 1780259-94-0 | 50mg | $348 | 2021-12-16 | Buy |
ZK756326(dihydrochloride) Chemical Properties,Uses,Production
Uses
ZK756326 dihydrochloride is a nonpeptide chemokine receptor agonist for the CC chemokine receptor CCR8.
IC 50
CCR8: 1.8 μM (IC50, in U87 cells); 5-HT2B: 4.4 μM (IC50); 5-HT1A: 5.4 μM (IC50); 5-HT6: 5.9 μM (IC50); 5-HT5A: 16 μM (IC50); 5-HT2C: 34.8 μM (IC50); α2A: <20 μM (IC50)
References
[1] Haskell CA, et al. Identification and characterization of a potent, selective nonpeptide agonist of the CC chemokine receptor CCR8. Mol Pharmacol. 2006 Jan;69(1):309-16. DOI:10.1124/mol.105.014779
ZK756326(dihydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
ZK756326(dihydrochloride) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Changzhou Chenhong Biotechnology Co., Ltd. | 0519-85788828 13775037613 | sales@chemrenpharm.com | China | 3600 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8011 | 62 |
| Shanghai Chaolan Chemical Technology Center | 021-QQ：65489617 15618227136 | Sales@ATKchemical.com | China | 9342 | 58 |