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ChemicalBook >> CAS DataBase List >>Carboxyatractyloside

Carboxyatractyloside

CAS No.
77228-71-8
Chemical Name:
Carboxyatractyloside
Synonyms
Carboxyatractyloside, 10 mM in DMSO;Carboxyatractylosidetripotassiumsal;Carboxyatractyloside tripotassium salt;Carboxyatractyloside potassium salt - Bio-X ?;Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-;(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid
CBNumber:
CB62677293
Molecular Formula:
C31H46O18S2
Molecular Weight:
770.81
MDL Number:
MFCD00152201
MOL File:
77228-71-8.mol
Last updated:2025-04-28 21:36:36

Carboxyatractyloside Properties

Density 1.58±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility H2O: ≥10mg/mL
pka -3?+-.0.18(Predicted)
form solid
color white
optical activity [α]/D -34 to -48°, c =0.5 in water
biological source Xanthium sibiricum
Water Solubility H2O: ≥10mg/mL
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301+H311+H331
Precautionary statements  P261-P264-P280-P301+P310-P302+P352+P312-P304+P340+P311
Hazard Codes  T
Risk Statements  23/24/25
Safety Statements  36/37-45
RIDADR  UN 2811 6.1 / PGI
WGK Germany  3

Carboxyatractyloside price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C4992 Carboxyatractyloside potassium salt ≥98% (HPLC), from 77228-71-8 2mg $199 2023-01-07 Buy
ChemScene CS-0017047 Carboxyatractyloside 77228-71-8 5mg $250 2021-12-16 Buy
AvaChem 3202A Carboxyatractyloside 77228-71-8 10mg $290 2021-12-16 Buy
Arctom AS713545 Carboxyatractyloside ≥98% 77228-71-8 100mg $342 2021-12-16 Buy
Crysdot CD11059260 Carboxyatractylosidetripotassiumsalt 97% 77228-71-8 10mg $380 2021-12-16 Buy
Product number Packaging Price Buy
C4992 2mg $199 Buy
CS-0017047 5mg $250 Buy
3202A 10mg $290 Buy
AS713545 100mg $342 Buy
CD11059260 10mg $380 Buy

Carboxyatractyloside Chemical Properties,Uses,Production

Uses

Carboxyatractyloside potassium salt has been used as an activator of Ca2+-induced mPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) opening. It has also been used as a adenine nucleotide translocator (ANT) inhibitor to study the inhibition of oxidative phosphorylation in intact T98G glioma cells.

Biochem/physiol Actions

Carboxyatractyloside is a highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carrier; i.e. adenine nucleotide translocase (ANT); causes stabilization of the c conformation of ANT leading to permeability transition pore (PTP) opening, loss of mitochondrial membrane potential, and apoptosis.

target

Calcium Channel | P450 (e.g. CYP17)

Carboxyatractyloside Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 135)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
Chengdu Greenpure Biopharma CO.,Ltd
18283602253; +8618283602253 jancyzheng@gcgreenpure.com China 953 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897 sales@biopurify.com China 3772 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29808 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32222 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10244 58

View Lastest Price from Carboxyatractyloside manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Carboxyatractyloside pictures 2025-04-28 Carboxyatractyloside
77228-71-8
US $64.00-160.00 / mg 99.83% 10g TargetMol Chemicals Inc.
Carboxyatractyloside Potassium Salt pictures 2023-02-24 Carboxyatractyloside Potassium Salt
77228-71-8
US $0.00 / mg 20mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
Carboxyatractyloside tripotassium salt pictures 2020-01-10 Carboxyatractyloside tripotassium salt
77228-71-8
US $9.80 / KG 1KG ≥98% 20 tons Career Henan Chemical Co
(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid Carboxyatractyloside tripotassium salt Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)- Carboxyatractylosidetripotassiumsal Carboxyatractyloside, 10 mM in DMSO Carboxyatractyloside potassium salt - Bio-X ? 77228-71-8 C31H46O18S2 reagent standard substance chemical reagent herbal extract pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM).