Carboxyatractyloside
- CAS No.
- 77228-71-8
- Chemical Name:
- Carboxyatractyloside
- Synonyms
- Carboxyatractyloside, 10 mM in DMSO;Carboxyatractylosidetripotassiumsal;Carboxyatractyloside tripotassium salt;Carboxyatractyloside potassium salt - Bio-X ?;Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-;(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid
- CBNumber:
- CB62677293
- Molecular Formula:
- C31H46O18S2
- Molecular Weight:
- 770.81
- MDL Number:
- MFCD00152201
- MOL File:
- 77228-71-8.mol
Density | 1.58±0.1 g/cm3(Predicted) |
---|---|
storage temp. | -20°C |
solubility | H2O: ≥10mg/mL |
pka | -3?+-.0.18(Predicted) |
form | solid |
color | white |
optical activity | [α]/D -34 to -48°, c =0.5 in water |
biological source | Xanthium sibiricum |
Water Solubility | H2O: ≥10mg/mL |
UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS06 |
---|---|
Signal word | Danger |
Hazard statements | H301+H311+H331 |
Precautionary statements | P261-P264-P280-P301+P310-P302+P352+P312-P304+P340+P311 |
Hazard Codes | T |
Risk Statements | 23/24/25 |
Safety Statements | 36/37-45 |
RIDADR | UN 2811 6.1 / PGI |
WGK Germany | 3 |
Carboxyatractyloside price More Price(14)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C4992 | Carboxyatractyloside potassium salt ≥98% (HPLC), from | 77228-71-8 | 2mg | $199 | 2023-01-07 | Buy |
ChemScene | CS-0017047 | Carboxyatractyloside | 77228-71-8 | 5mg | $250 | 2021-12-16 | Buy |
AvaChem | 3202A | Carboxyatractyloside | 77228-71-8 | 10mg | $290 | 2021-12-16 | Buy |
Arctom | AS713545 | Carboxyatractyloside ≥98% | 77228-71-8 | 100mg | $342 | 2021-12-16 | Buy |
Crysdot | CD11059260 | Carboxyatractylosidetripotassiumsalt 97% | 77228-71-8 | 10mg | $380 | 2021-12-16 | Buy |
Carboxyatractyloside Chemical Properties,Uses,Production
Uses
Carboxyatractyloside potassium salt has been used as an activator of Ca2+-induced mPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) opening. It has also been used as a adenine nucleotide translocator (ANT) inhibitor to study the inhibition of oxidative phosphorylation in intact T98G glioma cells.
Biochem/physiol Actions
Carboxyatractyloside is a highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carrier; i.e. adenine nucleotide translocase (ANT); causes stabilization of the c conformation of ANT leading to permeability transition pore (PTP) opening, loss of mitochondrial membrane potential, and apoptosis.
target
Calcium Channel | P450 (e.g. CYP17)
Carboxyatractyloside Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | jancyzheng@gcgreenpure.com | China | 953 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32222 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10244 | 58 |
View Lastest Price from Carboxyatractyloside manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-04-28 | Carboxyatractyloside
77228-71-8
|
US $64.00-160.00 / mg | 99.83% | 10g | TargetMol Chemicals Inc. | ||
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2023-02-24 | Carboxyatractyloside Potassium Salt
77228-71-8
|
US $0.00 / mg | 20mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
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2020-01-10 | Carboxyatractyloside tripotassium salt
77228-71-8
|
US $9.80 / KG | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- Carboxyatractyloside
77228-71-8
- US $64.00-160.00 / mg
- 99.83%
- TargetMol Chemicals Inc.
-
- Carboxyatractyloside Potassium Salt
77228-71-8
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- Carboxyatractyloside tripotassium salt
77228-71-8
- US $9.80 / KG
- ≥98%
- Career Henan Chemical Co