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(2α,17S,19E)-17-Acetoxy-19,20-didehydroajmalan-16-carboxylic acid methyl ester

CAS No.
912-27-6
Chemical Name:
(2α,17S,19E)-17-Acetoxy-19,20-didehydroajmalan-16-carboxylic acid methyl ester
Synonyms
Vincamedine;(2α,17S,19E)-17-Acetoxy-19,20-didehydroajmalan-16-carboxylic acid methyl ester
CBNumber:
CB62306470
Molecular Formula:
C24H28N2O4
Molecular Weight:
408.49012
MDL Number:
MOL File:
912-27-6.mol

(2α,17S,19E)-17-Acetoxy-19,20-didehydroajmalan-16-carboxylic acid methyl ester Properties

Melting point 185°C

(2α,17S,19E)-17-Acetoxy-19,20-didehydroajmalan-16-carboxylic acid methyl ester Chemical Properties,Uses,Production

Description

This carboline alkaloid has been isolated from Vinca difformis and V. minor and yields colourless prisms when crystallized from cydohexane. It is laevorotatory with [α]20D - 66° (c 0.52, CHCL3) or - 75° (c 1.0, CHCL3).

References

Janot, LeMen, Hammouda., Compt. rend., 243,85 (1956) Gosset, LeMen, Janot., Bull. Soc. Chim. Fr., 1033 (1961) Trojanek, Hodkova., Collect. Czech. Chem. Commun., 27,2981 (1962)

(2α,17S,19E)-17-Acetoxy-19,20-didehydroajmalan-16-carboxylic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

(2α,17S,19E)-17-Acetoxy-19,20-didehydroajmalan-16-carboxylic acid methyl ester Vincamedine 912-27-6