ChemicalBook >> CAS DataBase List >>OPB-171775
OPB-171775
- CAS No.
- 2131210-15-4
- Chemical Name:
- OPB-171775
- Synonyms
- OPB-171775
- CBNumber:
- CB614498633
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Last updated:2025-04-18 09:51:20
OPB-171775 Chemical Properties,Uses,Production
Uses
OPB-171775 is a molecular glue, which forms ternary complex with phosphodiesterase 3A (PDE3A) and schlafen family member 12 (SLFN12). OPB-171775 causes SLFN12 RNase-mediated cell death, activates SLFN12 RNase-associated GCN2 signaling pathway, and exhibits antitumor efficacy[1].
References
[1] Takaki EO, et al., A PDE3A-SLFN12 Molecular Glue Exhibits Significant Antitumor Activity in TKI-Resistant Gastrointestinal Stromal Tumors. Clin Cancer Res. 2024 Jun 12. DOI:10.1158/1078-0432.CCR-24-0096
OPB-171775 Preparation Products And Raw materials
Raw materials
Preparation Products
OPB-171775 Suppliers
Global( 7)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Chenrui Biotechnology Co. LTD | 17625585511 | 1580084073@qq.com | China | 809 | 58 |
| Hubei Weideli Chemical Reagent Co.，Ltd. | 13339985473 | C13339985473@163.com | China | 4911 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5636 | 58 |
| Soochow Chirally Material Science and Technology Co.,Ltd | 0512-66834346 17751187418 | szkrl2022@126.com | China | 890 | 58 |
| Hubei wei shi reagent group ltd., company | 027-59101766 13125137661 | 2853877621@qq.com | China | 8011 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. | 025-66061636 18013972705 | qqyang@aikonchem.com | China | 10152 | 58 |
| Selleck Chemicals | 400-668-6834 | info@selleck.cn | China | 12071 | 58 |
OPB-171775
2131210-15-4