ChemicalBook >> CAS DataBase List >>INDEX NAME NOT YET ASSIGNED
INDEX NAME NOT YET ASSIGNED
- CAS No.
- 2098181-84-9
- Chemical Name:
- INDEX NAME NOT YET ASSIGNED
- Synonyms
- CBNumber:
- CB611694335
- Molecular Formula:
- C108H182N44O25S2
- Molecular Weight:
- 2561.02
- MDL Number:
- MOL File:
- 2098181-84-9.mol
Last updated:2024-07-02 08:55:12
INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production
Biological Activity
KRpep-2d is a potent K-Ras inhibitor and inhibits proliferation of K-Ras-driven cancer cells. KRpep-2d can be used for cancer research[1]. KRpep-2d has cyclic structure with importance for K-Ras inhibitory activity. Leu77 , Ile9 and Asp12 are critical amino acid residues for the K-Ras inhibitory activity of KRpep-2d[1]. KRpep-2d (10-30 μM) has inhibitory activity of A427 cells with the proliferation rates of 68.3% (10 μM) and 48.3% (10 μM)[1].
References
[1]. Niida A, et al. Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2757-2761.
INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials
Raw materials
Preparation Products
INDEX NAME NOT YET ASSIGNED Suppliers
Global( 8)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2943 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52924 | 58 |
| Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5223 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | Eric@peptidego.com | China | 7071 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24644 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 6628 | 58 |
| Shanghai HongTide Biotechnology Co.,Ltd. | 19961912513 | sales@hongtide.com | China | 4604 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5127 | 58 |
2098181-84-9
C108H182N44O25S2