ChemicalBook >> CAS DataBase List >>tert-Butyl diethylphosphonoacetate
tert-Butyl diethylphosphonoacetate
- CAS No.
- 27784-76-5
- Chemical Name:
- tert-Butyl diethylphosphonoacetate
- Synonyms
- tert-butyl 2-(diethoxyphosphoryl)acetate;tert-Butyl diethylph;DIETHYL (BOC-METHYL)PHOSPHONATE;T-BUTYL DIETHYL PHOSPHONOACETATE;Tert-buty diethylphosphonoacetate;tert-Butyl diethylphosponoacetate;Tert-butyl diethylphosphonoactate;TERT-BUTYL DIETHYLPHOSPHONOACETATE;Tert-butyl diehylphosphonoacetate;Tert-butyl diethyl phosphonylacetate
- CBNumber:
- CB5708211
- Molecular Formula:
- C10H21O5P
- Molecular Weight:
- 252.24
- MDL Number:
- MFCD00075414
- MOL File:
- 27784-76-5.mol
- MSDS File:
- SDS
Last updated:2024-10-30 18:52:02
| Boiling point | 100-103 °C/1.5 mmHg (lit.) |
|---|---|
| Density | 1.074 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Liquid |
| Specific Gravity | 1.074 |
| color | Clear colorless |
| Water Solubility | Not miscible or difficult to mix in water. |
| BRN | 2050126 |
| InChI | InChI=1S/C10H21O5P/c1-6-13-16(12,14-7-2)8-9(11)15-10(3,4)5/h6-8H2,1-5H3 |
| InChIKey | NFEGNISFSSLEGU-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)CP(OCC)(OCC)=O |
| CAS DataBase Reference | 27784-76-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280a-P305+P351+P338-P321-P332+P313-P337+P313 | |||||||||
| Risk Statements | 36/38 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29319090 | |||||||||
| NFPA 704 |
|
tert-Butyl diethylphosphonoacetate price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 348333 | tert-Butyl diethylphosphonoacetate 95% | 27784-76-5 | 5g | $114 | 2023-01-07 | Buy |
| TCI Chemical | B2814 | tert-Butyl Diethylphosphonoacetate >97.0%(GC) | 27784-76-5 | 1g | $28 | 2024-03-01 | Buy |
| TCI Chemical | B2814 | tert-Butyl Diethylphosphonoacetate >97.0%(GC) | 27784-76-5 | 5g | $80 | 2024-03-01 | Buy |
| Alfa Aesar | L17651 | tert-Butyl diethylphosphonoacetate, 95% | 27784-76-5 | 5g | $90.65 | 2024-03-01 | Buy |
| Alfa Aesar | L17651 | tert-Butyl diethylphosphonoacetate, 95% | 27784-76-5 | 1g | $29.7 | 2021-12-16 | Buy |
tert-Butyl diethylphosphonoacetate Chemical Properties,Uses,Production
Chemical Properties
Clear colorless liquid
Uses
tert-Butyl diethylphosphonoacetate is used as a reactant for preparation of hydroxymethylated dihydroxyvitamin D3 analogs via Wittig-Horner approach, as potential antitumor agents, synthesis of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat 3) and bicyclic triaminophosphine-promoted stereoselective synthesis of a,?-unsaturated esters, fluorides, and nitriles from aldehydes and ketones using Wadsworth-Emmons phosphonates
Synthesis
Triethyl phosphite (485 g) is warmed up to 90°C under N2 atmosphere in a three-necked round-bottomed flask, and /-butyl bromoacetate (541 g) is added dropwise into the system within 2 h. Then, the mixture is stirred at 90°C for around 4 hours and cooled to room temperature. The obtained mixture is distilled under vacuo to remove compounds with low boiling points, and the residue is collected as a colorless liquid tert-butyl diethylphosphonoacetate in 97 percent yield (680 g).
tert-Butyl diethylphosphonoacetate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 294)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangxi Sunway Chemical Co., Ltd. | +86-0794-5259909 +8615888611133 | dave@jxswchem.com | China | 22 | 58 |
| Jiangxi Sunway Chemical Co., Ltd. | +86-0794-5259909 +8615888611133 | dave@jxswchem.com | China | 22 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18275 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 998 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18648 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21639 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29886 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 19943 | 58 |
View Lastest Price from tert-Butyl diethylphosphonoacetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-30 | tert-Butyl diethylphosphonoacetate
27784-76-5
|
US $0.00 / KG | 1KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd | |
 |
2023-11-01 | tert-Butyl diethylphosphonoacetate
27784-76-5
|
US $0.00-0.00 / kg | 0.10000000149011612kg | 99.0%min | 200kg | Hangzhou ICH Biofarm Co., Ltd | |
 |
2023-06-26 | tert-Butyl 2-(diethoxyphosphoryl)acetate
27784-76-5
|
US $200.00 / kg | 10kg | 99% | 500kg/month | Hebei Mingeng Biotechnology Co., Ltd |
-
- tert-Butyl diethylphosphonoacetate
27784-76-5
- US $0.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- tert-Butyl diethylphosphonoacetate
27784-76-5
- US $0.00-0.00 / kg
- 99.0%min
- Hangzhou ICH Biofarm Co., Ltd
-
- tert-Butyl 2-(diethoxyphosphoryl)acetate
27784-76-5
- US $200.00 / kg
- 99%
- Hebei Mingeng Biotechnology Co., Ltd
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tert-Butyl diethylphosponoacetate
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tert-Butyl Diethylphosphonoacetate >
Tert-butyl diethyl phosphonylacetate
TERT-BUTYL DIETHYLPHOSPHONOACETATE (27784-76-5)
tert-butyl 2-(diethoxyphosphoryl)acetate
1,1-Dimethylethyl 2-(diethoxyphosphinyl)acetate
ert-butyl2-diethoxyphosphorylacetate
Diethyl phosphonoyl acetate tert butyl ester
27784-76-5
C2H5O2POCH2CO2CCH33
Horner-Wadsworth-Emmons Reagents
Olefination
Synthetic Reagents
C-C Bond Formation
C-C Bond Formation
Horner-Wadsworth-Emmons Reagents
Olefination
27784-76-5