ChemicalBook >> CAS DataBase List >>Bis(trimethylsilyl)trifluoroacetamide
Bis(trimethylsilyl)trifluoroacetamide
- CAS No.
- 25561-30-2
- Chemical Name:
- Bis(trimethylsilyl)trifluoroacetamide
- Synonyms
- BSTFA;N,O-BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE;Trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate;N,O-BSTFA;N,O-Bis(Trimethylsilyl);N.O-Bis(trimethylsilyl)trifluoro acetamide (BSTFA);n,o-bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane;N,O-Bis(trimethylsilyl)trifluoroacetamide, contains 1% TMCS, ampuled under argon;bstfa kit;REGISIL RC-1
- CBNumber:
- CB5464744
- Molecular Formula:
- C8H18F3NOSi2
- Molecular Weight:
- 257.4
- MDL Number:
- MFCD00008269
- MOL File:
- 25561-30-2.mol
- MSDS File:
- SDS
Last updated:2024-10-23 13:36:13
| Melting point | -10°C |
|---|---|
| Boiling point | 45-50 °C14 mm Hg(lit.) |
| Density | 0.97 g/mL(lit.) |
| refractive index |
n |
| Flash point | 75 °C |
| storage temp. | 2-8°C |
| solubility | Miscible with chloroform. |
| form | Liquid |
| pka | 1.82±0.50(Predicted) |
| Specific Gravity | 0.971 |
| color | Colorless to pale yellow |
| Water Solubility | hydrolyses |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| Sensitive | Moisture Sensitive |
| BRN | 3607620 |
| Stability | Moisture Sensitive |
| InChIKey | XCOBLONWWXQEBS-KPKJPENVSA-N |
| CAS DataBase Reference | 25561-30-2(CAS DataBase Reference) |
| FDA UNII | 5T8NA426KZ |
| NIST Chemistry Reference | Bis(trimethylsilyl)trifluoroacetamide(25561-30-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H302-H314 | |||||||||
| Precautionary statements | P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | C,F,T | |||||||||
| Risk Statements | 11-34-10-35-14 | |||||||||
| Safety Statements | 26-36/37/39-45-16 | |||||||||
| RIDADR | UN 2924 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| Hazard Note | Flammable/Moisture Sensitive | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29310095 | |||||||||
| NFPA 704 |
|
Bis(trimethylsilyl)trifluoroacetamide price More Price(80)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B-023 | BSTFA (with 1% TMCS) kit of 10 × 1?mL, analytical standard, Cerilliant? | 25561-30-2 | 10x1mL | $98.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | 15222 | N,O-Bis(trimethylsilyl)trifluoroacetamide for GC derivatization, LiChropur?, ≥99.0% | 25561-30-2 | 1mL | $30.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | 15222 | N,O-Bis(trimethylsilyl)trifluoroacetamide for GC derivatization, LiChropur?, ≥99.0% | 25561-30-2 | 5ml | $78.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | 15222 | N,O-Bis(trimethylsilyl)trifluoroacetamide for GC derivatization, LiChropur?, ≥99.0% | 25561-30-2 | 25mL | $195 | 2024-03-01 | Buy |
| Sigma-Aldrich | 15222 | N,O-Bis(trimethylsilyl)trifluoroacetamide for GC derivatization, LiChropur?, ≥99.0% | 25561-30-2 | 10x1mL | $286 | 2024-03-01 | Buy |
Bis(trimethylsilyl)trifluoroacetamide Chemical Properties,Uses,Production
Uses
Used for synthesis of pharmaceutical intermediates.
Chemical Properties
Clear to yellowish clear liquid
Uses
Used as a reactant in the preparation of pyrimidinone ribosides and analogs that show anti-tumor properties.
Uses
N,O-bis(trimethylsilyl)-trifluoroacetamide (BSTFA) is similar to BSA in specificity of modification and there are several studies which have used both reagents.One study found BSTFA superior to BSA in product stability and yield of derivative. Another study compared several trimethylsilyl donors for end-capping of silica and observed that BSTFA was more reactive than BSA but less reactive than TMCim. Both BSA and BSTFA were used to prepare trimethylsilyl derivatives of pyrimidines and purines.Current work has used BSTFA for metabolomics analysis of urine,for the measurement of khatamines (psychoactive amines of khat (Catha edulis Forsk), and for the measurement of acrylamide in cocoa.
Uses
N,O-Bis(trimethylsilyl)trifluoroacetamide is used for analytical purposes or as a chemical reagent for synthesis of more complex molecules. It is silylation reagent useful in GC and GC-MS for the derivatization of a wide range of functional groups under mild conditions. It is also used as DAT inhibitor and a SLC6A2 inhibitor. It is routinely used to derivatize carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids and amides.
Definition
ChEBI: A silyl ether that is the N,O-bis(trimethylsilyl) derivative of trifluoroacetamide. N,O-bis(trimethylsilyl)trifluoroacetamide is a derivatisation agent used in gas chromatography/m ss spectrometry applications.
General Description
N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane has found application to be used in gas chromatography (GC) and mass-spectrometry (MS). It can also be used in HPLC- electrochemical detection assay of 8-oxo-deoxyguanosine and?8-oxo-guanine.
Bis(trimethylsilyl)trifluoroacetamide Preparation Products And Raw materials
Global( 541)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20287 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
| Hebei Mojin Biotechnology Co.,Ltd | +86-15028179902 | angelia@hbmojin.com | China | 1178 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18747 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Fluoropharm Co., Ltd. | +86-0571-85586753; +8613336034509 | sales@fluoropharm.com | China | 1376 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32951 | 60 |
| Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 988 | 58 |
| Tianjin Zhongxin Chemtech Co., Ltd. | +86-022-66880623 +8618622897568 | sales@tjzxchem.com | China | 563 | 58 |
View Lastest Price from Bis(trimethylsilyl)trifluoroacetamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-14 | Bis(trimethylsilyl)trifluoroacetamide
25561-30-2
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-10-24 | BSTFA-TMCS
25561-30-2
|
US $33.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2024-10-15 | bis(trimethylsilyl)trifluoroacetamide
25561-30-2
|
US $0.00-0.00 / Kg | 1Kg | 99.9% | 200tons | airuikechemical co., ltd. |
-
- Bis(trimethylsilyl)trifluoroacetamide
25561-30-2
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- BSTFA-TMCS
25561-30-2
- US $33.00 / mg
- TargetMol Chemicals Inc.
-
- bis(trimethylsilyl)trifluoroacetamide
25561-30-2
- US $0.00-0.00 / Kg
- 99.9%
- airuikechemical co., ltd.
25561-30-2(Bis(trimethylsilyl)trifluoroacetamide)Related Search:
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BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE, 9 9+%, DERIVATIZATION GRADE
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BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE*(B STFA) WITH
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N,O-BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE WITH TRIMETHYLCHLOROSILANE, 98% (EXCLUDING TMCS)
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N,O-BIS(TRIMETHYLSILYL)TRIFLUOROACET-AMI DE WITH 1% TMCS
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N.O-Bis(Trimethylsilyl)Trifluoroacetamide(Bstfa),Finasteride
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BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE WITH 10%TMCS
BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE(BSTFA)
N,O-Bis(trimethylsilyl)trifluoroacetamide99+%
N,O-Bis(trimethylsilyl)trifluoroacetamide, packaged in 1 ml ampules, 98%
N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% trimethylsilyl chloride
N,0-Bis(trimethylsilyl)trifluoroacetamideBSTFA
bstfa + tmcs
bstfa kit
2,2,2-Trifluoro-1-trimethylsiloxy-N-trimethylsilylethanimine
2,2,2-Trifluoro-N-(trimethylsilyl)acetimidic acid trimethylsilyl ester
2,2,2-Trifluoro-N-(trimethylsilyl)ethanimidic acid trimethylsilyl ester
N-(Trimethylsilyl)-1-(trimethylsilyloxy)-2,2,2-trifluoroethanimine
N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal^t bottles
N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal
N,O-Bis(trimethylsilyl)trifluoroacetamide, 99+%, packaged under Argon in resealable ChemSeal^t bottl
BSTFA-TMCS (99:1) [Derivatizing Reagent for GC]
BSTFA [=N,O-Bis(trimethylsilyl)trifluoroacetamide]
N,O-Bis(trimethylsilyl)trifluoroacetamide ,97.5%
N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane,BSTFA + TMCS, Silylating mixture Fluka V
N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane,BSTFA + TMCS
BSTFA (with 1% TMCS), 10 amps.
N,O-Bis(trimethylsilyl)trifluoroacetamide, packaged in 1 ml ampoules, 98%
N,O-Bis(trimethylsilyl)trifluoroacetamide derivatization grade
N,O-Bis(trimethylsilyl)trifluoroacetamide, 99+%, packaged under Argon in resealable ChemSeal^t bottles
BSTFA (with 1% TMCS)
Trimethylsilyl (1Z)-2,2,2-trifluoro-N-[(Z)-trimethylsilyl]ethanimidoate
LABOTEST-BB LT00453960
BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE
BIS(TRIMETHYL)TRIFLUOROACETAMIDE
N,N-BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE
SILYLATING MIXTURE FLUKA V
REGISIL RC-1
REGISIL RC-2