TiMcodar
- CAS No.
- 179033-51-3
- Chemical Name:
- TiMcodar
- Synonyms
- VX-853;VX 853;TiMcodar;Timcodar ,VX-853;TimcodarQ: What is Timcodar Q: What is the CAS Number of Timcodar;(2S)-N-benzyl-3-(4-chlorophenyl)-N-(1,5-dipyridin-4-ylpentan-3-yl)-2-[methyl-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]amino]propanamide;Benzenepropanamide, 4-chloro-α-[methyl[2-(3,4,5-trimethoxyphenyl)-2-oxoacetyl]amino]-N-(phenylmethyl)-N-[3-(4-pyridinyl)-1-[2-(4-pyridinyl)ethyl]propyl]-, (αS)-
- CBNumber:
- CB52611403
- Molecular Formula:
- C43H45ClN4O6
- Molecular Weight:
- 749.29
- MDL Number:
- MFCD00948808
- MOL File:
- 179033-51-3.mol
| Boiling point | 878.7±75.0 °C(Predicted) |
|---|---|
| Density | 1.230±0.06 g/cm3(Predicted) |
| pka | 6.28±0.10(Predicted) |
| NCI Dictionary of Cancer Terms | VX 853 |
| FDA UNII | U141W322WZ |
TiMcodar Chemical Properties,Uses,Production
Uses
Timcodar is a macrolide agent, and studies have shown that during adipogenesis, timcodar can significantly inhibit fat accumulation, with an effect similar to that of rapamycin. However, unlike rapamycin, timcodar does not cause immunosuppression and glucose resistance. In addition, timcodar can effectively inhibit the adipogenic transcriptional regulators PPAR?? and C/EBP??, thereby inhibiting genes involved in fat accumulation. These studies lay the foundation for timcodar as a potential anti-obesity therapy, as obesity is becoming a global epidemic.
References
[1] Timcodar (VX‐853) Is a Non‐FKBP12 Binding Macrolide Derivative That Inhibits PPARγ and Suppresses Adipogenesis
TiMcodar Preparation Products And Raw materials
Raw materials
Preparation Products
TiMcodar Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12335 | 58 |
| Suzhou Meishi Biotechnology Co., Ltd. | 1173954148q | meishipharma@126.com | China | 20033 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19956 | 58 |
