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ChemicalBook >> CAS DataBase List >>1H-Inden-1-one, 2,3-dihydro-7-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-, (2E)-

1H-Inden-1-one, 2,3-dihydro-7-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-, (2E)-

CAS No.
2054199-25-4
Chemical Name:
1H-Inden-1-one, 2,3-dihydro-7-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-, (2E)-
Synonyms
TNF-α-IN-9;1H-Inden-1-one, 2,3-dihydro-7-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-, (2E)-
CBNumber:
CB512028503
Molecular Formula:
C17H14O4
Molecular Weight:
282.29
MDL Number:
MOL File:
2054199-25-4.mol
Last updated:2025-04-18 09:52:24

1H-Inden-1-one, 2,3-dihydro-7-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-, (2E)- Properties

Boiling point 555.3±50.0 °C(Predicted)
Density 1.386±0.06 g/cm3(Predicted)
pka 7.67±0.20(Predicted)

1H-Inden-1-one, 2,3-dihydro-7-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-, (2E)- Chemical Properties,Uses,Production

Uses

TNF-α-IN-9 (compound 48) is a analog of NDM-1 inhibitor-3 (HY-150758). TNF-α-IN-9 is a TNF-α inhibitor. TNF-α-IN-9 shows low inhibitory activity[1].

References

[1] Kadayat TM, et al. Discovery and structure-activity relationship studies of 2-benzylidene-2,3-dihydro-1H-inden-1-one and benzofuran-3(2H)-one derivatives as a novel class of potential therapeutics for inflammatory bowel disease. Eur J Med Chem. 2017 Sep 8;137:575-597. DOI:10.1016/j.ejmech.2017.06.018

1H-Inden-1-one, 2,3-dihydro-7-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-, (2E)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Inden-1-one, 2,3-dihydro-7-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-, (2E)- Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32222 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71829 60
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136 Sales@ATKchemical.com China 9342 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9409 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19784 58
Sangon Biotech (Shanghai) Co.,Ltd. 400-821-026 Sales@sangon.com China 47255 58

View Lastest Price from 1H-Inden-1-one, 2,3-dihydro-7-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-, (2E)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TNF-α-IN-9 pictures 2024-11-19 TNF-α-IN-9
2054199-25-4
 US $68.00-225.00 / mg 98.28% 10g TargetMol Chemicals Inc.
  • TNF-α-IN-9 pictures
  • TNF-α-IN-9
    2054199-25-4
  • US $68.00-225.00 / mg
  • 98.28%
  • TargetMol Chemicals Inc.
1H-Inden-1-one, 2,3-dihydro-7-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-, (2E)- TNF-α-IN-9 2054199-25-4