5-Chloro-8-hydroxyquinoline
- CAS No.
- 130-16-5
- Chemical Name:
- 5-Chloro-8-hydroxyquinoline
- Synonyms
- Cloxyquin;Cloxiquin;cloxiquine;5-CHLORO-8-QUINOLINOL;Cloxyqui;Chlorisept;Cloxyquine;Dermofungin;DERMOFONGIN;5-CHLOROOXINE
- CBNumber:
- CB4434834
- Molecular Formula:
- C9H6ClNO
- Molecular Weight:
- 179.6
- MDL Number:
- MFCD00006788
- MOL File:
- 130-16-5.mol
- MSDS File:
- SDS
| Melting point | 122-124 °C(lit.) |
|---|---|
| Boiling point | 348.7±22.0 °C(Predicted) |
| Density | 1.2364 (rough estimate) |
| vapor pressure | 0.003Pa at 25℃ |
| refractive index | 1.5330 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 0.019g/l (experimental) |
| form | Powder |
| pka | 3.77±0.10(Predicted) |
| color | Light green to gray |
| Sensitive | Light Sensitive |
| Merck | 14,2422 |
| BRN | 5289 |
| InChIKey | RWPWQYXFGFYJBA-UHFFFAOYSA-N |
| CAS DataBase Reference | 130-16-5(CAS DataBase Reference) |
| FDA 21 CFR | 310.545 |
| EWG's Food Scores | 1 |
| FDA UNII | BPF36H1G6S |
| NIST Chemistry Reference | 8-Quinolinol, 5-chloro-(130-16-5) |
| EPA Substance Registry System | 8-Quinolinol, 5-chloro- (130-16-5) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335-H410 | |||||||||
| Precautionary statements | P261-P264-P271-P273-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VC4590000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29334990 | |||||||||
| NFPA 704 |
|
5-Chloro-8-hydroxyquinoline price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C47000 | 5-Chloro-8-quinolinol 95% | 130-16-5 | 100g | $68.6 | 2024-03-01 | Buy |
| TCI Chemical | C0645 | 5-Chloro-8-hydroxyquinoline >98.0%(GC)(T) | 130-16-5 | 25g | $36 | 2024-03-01 | Buy |
| TCI Chemical | C0645 | 5-Chloro-8-hydroxyquinoline >98.0%(GC)(T) | 130-16-5 | 250g | $158 | 2024-03-01 | Buy |
| Alfa Aesar | B22856 | 5-Chloro-8-hydroxyquinoline, 95% | 130-16-5 | 50g | $35.65 | 2024-03-01 | Buy |
| Alfa Aesar | B22856 | 5-Chloro-8-hydroxyquinoline, 95% | 130-16-5 | 250g | $88.65 | 2024-03-01 | Buy |
5-Chloro-8-hydroxyquinoline Chemical Properties,Uses,Production
Chemical Properties
light green to grey powder
Uses
Dermofungin, is an impurity of Cioquinol, which is an antifungal and antiprotozoal drug.
Uses
antibacterial, antifungal
Definition
ChEBI: Cloxiquine is a member of quinolines and an organochlorine compound.
Synthesis Reference(s)
The Journal of Organic Chemistry, 70, p. 8590, 2005 DOI: 10.1021/jo051191x
in vitro
Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.062 to 0.25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis .
Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner.|
Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells.
Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells.
in vivo
Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model.
Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model.
5-Chloro-8-hydroxyquinoline Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12789 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | allison@yan-xi.com | China | 5854 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 | sales01@tairunfaz.com | China | 8051 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18135 | 58 |
| airuikechemical co., ltd. | +86-18353166132 +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 19919 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29856 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2930 | 58 |
View Lastest Price from 5-Chloro-8-hydroxyquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-05-07 | 5-Chloro-8-hydroxyquinoline
130-16-5
|
US $30.00 / kg | 1kg | 0.99 | 100 tons | Hebei Fengjia New Material Co., Ltd | |
 |
2025-05-02 | Cloxiquine
130-16-5
|
US $31.00 / g | 99.87% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-05-01 | Cloxiquine
130-16-5
|
US $31.00 / g | 99.87% | 10g | TargetMol Chemicals Inc. |
-
- 5-Chloro-8-hydroxyquinoline
130-16-5
- US $30.00 / kg
- 0.99
- Hebei Fengjia New Material Co., Ltd
-
- Cloxiquine
130-16-5
- US $31.00 / g
- 99.87%
- TargetMol Chemicals Inc.
-
- Cloxiquine
130-16-5
- US $31.00 / g
- 99.87%
- TargetMol Chemicals Inc.
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