ChemicalBook >> CAS DataBase List >>Sumanirole maleate
Sumanirole maleate
- CAS No.
- 179386-43-7
- Chemical Name:
- Sumanirole maleate
- Synonyms
- Sumanirole;(5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one;4H-IMidazo[4,5,1-ij]quinolin-2(1H)-one,5,6-dihydro-5-(MethylaMino)-, (5R)-;(R)-5-(MethylaMino)-5,6-dihydro-1H-iMidazo[4,5,1-ij]quinolin-2(4H)-one Maleate,(free base);(R)-5,6-Dihydro-5-(MethylaMino)-4H-iMidazo[4,5,1-ij]quinolin- 2(1H)-one (2Z)-2-Butenedioate;(5R)-5,6-Dihydro-5-(MethylaMino)-4H-iMidazo[4,5,1-ij]quinolin-2(1H)-one (2Z)-2-Butenedioate
- CBNumber:
- CB42535698
- Molecular Formula:
- C11H13N3O
- Molecular Weight:
- 203.24
- MDL Number:
- MOL File:
- 179386-43-7.mol
Last updated:2023-06-26 08:28:20
Density | 1.32 |
---|---|
storage temp. | 2-8°C(protect from light) |
FDA UNII | 3E93IV1U45 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P280-P305+P351+P338 |
Sumanirole maleate price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
AK Scientific | 9411AA | (R)-5-(Methylamino)-5,6-dihydro-1H-imidazo[4,5,1-ij]quinolin-2(4H)-one | 179386-43-7 | 10mg | $232 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 42272 | Sumanirole maleate | 179386-43-7 | 5mg | $290 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0008147 | SUMANIROLE 95.00% | 179386-43-7 | 1G | $1575 | 2021-12-16 | Buy |
Alichem | 179386437 | (R)-5-(Methylamino)-5,6-dihydro-1H-imidazo[4,5,1-ij]quinolin-2(4H)-one | 179386-43-7 | 1g | $646.84 | 2021-12-16 | Buy |
Crysdot | CD11228820 | (R)-5-(Methylamino)-5,6-dihydro-1H-imidazo[4,5,1-ij]quinolin-2(4H)-one 95+% | 179386-43-7 | 1g | $772 | 2021-12-16 | Buy |
Sumanirole maleate Chemical Properties,Uses,Production
Chemical Properties
Off-White to Light Beige Solid
Uses
Sumanirole is a high affinity D2 receptor agonist (EC50 values are between 17 and 75 nM in cell-based assays). Sumanirole displays >200-fold selectivity for the D2 receptor against other dopamine rece ptor subtypes (Ki values are 9.0, 1940, >2190 and >7140 for D2, D3, D4 and D1 receptors respectively). Sumanirole exhibits antiParkinsonian activity similar to Ropinirole (R641000).
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Synthesis of Sumanirole maleate from (R)-benzyl 1-Methoxy-2-oxo-2,4,5,6-tetrahydro-1H-iMidazo[4,5,1-ij]quinolin-5-yl(Methyl)carbaMate
Sumanirole maleate Preparation Products And Raw materials
Raw materials
Preparation Products
Sumanirole maleate Suppliers
Global( 17)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
SPIRO PHARMA | eric_feng1954@126.com | China | 9248 | 55 | |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 +86-13028896684; | sales@rrkchem.com | China | 57423 | 58 |
Jiangsu aikang biomedical research and development co., LTD | 025-66110311 13155353615 | qzhang@aikonchem.com | China | 15527 | 58 |
Hefei fuya biotechnology co. LTD | 18096409024 | sales02@foreversyn.com | China | 1907 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44807 | 58 |
Shanghai Haohong Scientific Co., Ltd. | 400-400-8210725 17717813675; | malulu@leyan.com | China | 39990 | 58 |
Carbosynth | -- | sales@carbosynth.com | United Kingdom | 6005 | 58 |
(5R)-5,6-Dihydro-5-(MethylaMino)-4H-iMidazo[4,5,1-ij]quinolin-2(1H)-one (2Z)-2-Butenedioate
(R)-5,6-Dihydro-5-(MethylaMino)-4H-iMidazo[4,5,1-ij]quinolin-
2(1H)-one (2Z)-2-Butenedioate
(R)-5-(MethylaMino)-5,6-dihydro-1H-iMidazo[4,5,1-ij]quinolin-2(4H)-one Maleate,(free base)
4H-IMidazo[4,5,1-ij]quinolin-2(1H)-one,5,6-dihydro-5-(MethylaMino)-, (5R)-
(5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one
Sumanirole
179386-43-7