ChemicalBook >> CAS DataBase List >>Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester
Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester
- CAS No.
- 1620951-72-5
- Chemical Name:
- Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester
- Synonyms
- PA-1;PA1 2HCl;PA-1 2HCl,PA1 2HCl;Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester
- CBNumber:
- CB42350909
- Molecular Formula:
- C32H50O7Sn2
- Molecular Weight:
- 784.1552
- MDL Number:
- MOL File:
- 1620951-72-5.mol
Last updated:2025-04-18 09:52:15
Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester Chemical Properties,Uses,Production
Uses
PA1 is a photoswitchable epithelial sodium channel (ENaC) blocker. PA1 can switch to cis-PA1 at 400nm and trans-PA1 at 500nm. PA1 inhibits δ/αENaC, αβγENaC, and δβγENaC, with IC50 values of 4.3nM, 90 nM, and 390 nM, respectively[1].
References
[1] Matthias Sch?nberger, et al. Controlling epithelial sodium channels with light using photoswitchable amilorides. Nat Chem. 2014 Aug;6(8):712-9. DOI:10.1038/nchem.2004
Synthesis of Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester from Cyanamide and 4-AMINOAZOBENZENE and RARECHEM AL BO 1272
Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester Suppliers
Global( 28)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19905 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | Eric@peptidego.com | China | 7061 | 58 |
| Shanghai guandao biology engineering co., ltd | 18818239863 18818239863 | 3171921642@qq.com | China | 9201 | 58 |
| Wuhan Sunncell Biotech Co., Ltd. | 17764018385 | 1242926414@qq.com | China | 1855 | 58 |
| Shanghai Bolsen Biotechnology Co., LTD | 021-67681877 13166061152 | bioesn@163.com | China | 8234 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 9747 | 58 |
| JENNIO-LAB(GUANGDONG) LIFE SCIENCE TECHNOLOGY CENTER | 020-29185636 18802032712 | 2130357954@qq.com | China | 9792 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24863 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 6628 | 58 |
View Lastest Price from Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester manufacturers
Bis(3-methylsalicylic acid)1,1,3,3-tetrabutyl-1,3-distanna-2-oxapropane-1,3-diyl ester
PA-1
PA1 2HCl
PA-1 2HCl,PA1 2HCl
1620951-72-5