NCNP-01
- CAS No.
- 2055732-84-6
- Chemical Name:
- NCNP-01
- Synonyms
- NS-065;NCNP-01;Viltolarsen
- CBNumber:
- CB411075934
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| storage temp. | Store at -20°C |
|---|---|
| form | Solid |
| color | White to off-white |
| FDA UNII | SXA7YP6EKX |
NCNP-01 Chemical Properties,Uses,Production
Uses
Viltolarsen (NS-065/NCNP-01) is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen has the potential for Duchenne muscular dystrophy (DMD) research[1][2].
References
[1] Sohita Dhillon. Viltolarsen: First Approval. Drugs. 2020 Jul;80(10):1027-1031. DOI:10.1007/s40265-020-01339-3
[2] Naoki Watanabe, et al. NS-065/NCNP-01: An Antisense Oligonucleotide for Potential Treatment of Exon 53 Skipping in Duchenne Muscular Dystrophy. Mol Ther Nucleic Acids. 2018 Dec 7:13:442-449. DOI:10.1016/j.omtn.2018.09.017
NCNP-01 Preparation Products And Raw materials
Raw materials
Preparation Products
NCNP-01 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Apextide Co Ltd | +86-15300650552 +86-15300650552 | info@apextide.com | China | 92 | 58 |
| Lanxi Xingnuo Import and Export Trading Co., Ltd | +86-15888978871 +86-13901546477 | sales@xingnuotraders.com | China | 163 | 58 |
| Jiangsu Magic Biotechnology Co., Ltd | 13921770081 | svp01@magicbiotech.cn | China | 507 | 58 |
| Apextide Co Ltd | 15300650552 | info@apextide.com | China | 90 | 58 |
| Zhengzhou Runkai Pharmaceutical Technology Co., Ltd | 19137644811 | 3649307081@qq.com | China | 511 | 58 |
| Guangzhou Brand-new Changshi Pharmaceutical Biotechnology Co., Ltd | 19066311943 | 815989315@qq.com | China | 730 | 58 |