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ChemicalBook >> CAS DataBase List >>1-Phenoxy-2-propanol

1-Phenoxy-2-propanol

CAS No.
770-35-4
Chemical Name:
1-Phenoxy-2-propanol
Synonyms
PROPYLENE GLYCOL PHENYL ETHER;1-PHENOXYPROPAN-2-OL;Phenoxyisopropanol;DOWANOL®DOWANOL? PPh;AURORA KA-7000;1-Phenoxy-2-pr;DOWANOL(TM) PPH;PHENOXY PROPANOL;1-phenoxy-2-propano
CBNumber:
CB4100744
Molecular Formula:
C9H12O2
Molecular Weight:
152.19
MDL Number:
MFCD00016861
MOL File:
770-35-4.mol
MSDS File:
SDS
Last updated:2024-10-24 21:11:45

1-Phenoxy-2-propanol Properties

Melting point 11 °C
Boiling point 243 °C (lit.)
Density 1.064 g/mL at 20 °C (lit.)
vapor pressure 1Pa at 20℃
refractive index n20/D 1.523(lit.)
Flash point >230 °F
storage temp. Refrigerator
solubility water: soluble15.1g/L at 20°C
pka 14.43±0.20(Predicted)
form Oil
color Clear Colourless
Specific Gravity 1.051
Water Solubility 15.1g/L at 20℃
BRN 1941356
Stability Stable. Flammable. Incompatible with strong oxidizing agents.
LogP 1.41 at 24.1℃
CAS DataBase Reference 770-35-4(CAS DataBase Reference)
EWG's Food Scores 1-2
FDA UNII 87CZY0NY1A
NIST Chemistry Reference 1-Phenoxy-2-propanol(770-35-4)
EPA Substance Registry System 1-Phenoxy-2-propanol (770-35-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P280-P305+P351+P338-P337+P313
Hazard Codes  Xi
Risk Statements  36
Safety Statements  23-26
WGK Germany  1
RTECS  UB8886500
TSCA  Yes
HS Code  29094990
Toxicity LD50 orl-rat: 2830 mg/kg NTIS** OTS0539745
NFPA 704
1
1 0

1-Phenoxy-2-propanol price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 484423 1-Phenoxy-2-propanol ≥93% 770-35-4 1l $66.4 2024-03-01 Buy
TCI Chemical P0118 1-Phenoxy-2-propanol >95.0%(GC) 770-35-4 25mL $127 2024-03-01 Buy
TCI Chemical P0118 1-Phenoxy-2-propanol >95.0%(GC) 770-35-4 500mL $1155 2024-03-01 Buy
Alfa Aesar L04596 1-Phenoxy-2-propanol, tech. 85% 770-35-4 50g $33.65 2024-03-01 Buy
Alfa Aesar L04596 1-Phenoxy-2-propanol, tech. 85% 770-35-4 250g $128 2024-03-01 Buy
Product number Packaging Price Buy
484423 1l $66.4 Buy
P0118 25mL $127 Buy
P0118 500mL $1155 Buy
L04596 50g $33.65 Buy
L04596 250g $128 Buy

1-Phenoxy-2-propanol Chemical Properties,Uses,Production

Chemical Properties

colourless liquid

Uses

1-Phenoxy-2-propanol is a useful synthetic intermediate. It was used in the preparation of acylarylthiocarbamates as nonnucleoside reverse transcriptase inhibitors.

Uses

High-boiling solvent, bactericidal agent, fixa- tive for soaps and perfumes, intermediate for plas- ticizers.

Definition

Colorless liquid.Combustible.

Application

1-Phenoxy-2-propanol (PP) is used as a preservative in cosmetics. PP is currently permitted for up to 1% in cosmetic formulations in Korea and Europe. In addition to its cosmetic uses, PP is used as a solvent for mixing water and organic components in paints, coatings, and films. It is used as an ink solvent for industrial paints, ballpoint pens, stamp pads, and paint removers. The exposure range is broad since PP is used in various industrial paints and cosmetic

Synthesis Reference(s)

Tetrahedron Letters, 36, p. 9357, 1995 DOI: 10.1016/0040-4039(95)02027-M

General Description

1-Phenoxy-2-propanol (PP), a gycol ether, can be synthesized by reacting propylene oxide with phenol in the presence of Al2O3-MgO/Fe3O4 catalyst. The influence of its anesthetic property on gastropods has been analyzed. Its degradation by microorganisms in different soil types has been investigated.

Flammability and Explosibility

Non flammable

Safety Profile

Moderately toxic by ingestion and skin contact. Experimental reproductive effects. When heated to decompositionit emits acrid smoke and irritating vapors.

Toxicity evaluation

1-Phenoxy-2-propanol (PP) does not cause skin irritation or sensitization. However, it may induce mucosal irritation. The pregnant Himalayan rabbits were orally administered 0, 60, 180, and 540?mg/kg/day of PP during organogenesis (7–19 days of pregnancy). LOAEL (Lowest Observed Adverse Effect Level) for maternal toxicity was assessed at 540?mg/kg/day based on weight loss and apathy. In addition, LOAEL for developmental toxicity was 540?mg/kg/day, and NOAEL (No Observed Adverse Effect Level) was assessed at 180?mg/kg/day. The other study reported that NOAEL for maternal toxicity of PP orally treated to pregnant Wistar rats was 40?mg/kg/day, and NOAEL for developmental toxicity of PP was 160?mg/kg/day.

Regulations

1-Phenoxy-2-propanol (PP) has antibacterial properties and is designated as a sterilizing and preserving agent used in cosmetics and soaps. In Korea, PP comprises up to 1.0% of formulations and is only allowed in products that are washed off after use, and other products are prohibited. European Commission (EC) restricts washing products to 1.0% or less[1].

References

[1] Jung Dae Lee . “Percutaneous permeability of 1-phenoxy-2-propanol, a preservative in cosmetics.” Regulatory Toxicology and Pharmacology 103 (2019): Pages 56-62.

1-Phenoxy-2-propanol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 276)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12840 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5857 58
Nanjing Deda New Material Technology Co., Ltd 		+8613223293093 bella@njdeda.com China 80 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5893 58
Hebei Weibang Biotechnology Co., Ltd 		+8617732866630 bess@weibangbio.com China 18154 58
hebei hongtan Biotechnology Co., Ltd 		+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 970 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3002 58
Hebei Mojin Biotechnology Co.,Ltd 		+86-15028179902 angelia@hbmojin.com China 1178 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Shanxi Naipu Import and Export Co.,Ltd 		+86-13734021967 +8613734021967 kaia@neputrading.com China 1001 58

View Lastest Price from 1-Phenoxy-2-propanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Phenoxy-2-propanol pictures 2024-11-15 1-Phenoxy-2-propanol
770-35-4
 US $10.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
1-Phenoxy-2-propanol pictures 2024-11-15 1-Phenoxy-2-propanol
770-35-4
 US $2.00 / KG 1KG ≥99% 1000mt/year Jinan Finer Chemical Co., Ltd
1-Phenoxy-2-propanol pictures 2024-11-14 1-Phenoxy-2-propanol
770-35-4
 US $50.00 / kg 1kg 99% 1000 hebei hongtan Biotechnology Co., Ltd
DOWANOL? PPh 1-Phenoxy-2-propanol >=93% DOWANOL® 1-PHENOXY-2-PROPANOL (+/-)-1-PHENOXYPROPAN-2-OL 1-phenoxy-2-propano 2-Phenoxy-1-methylethanol 2-Propanol, 1-phenoxy- PROPYLENE PHENOXYTOL Propylenephenoxythol PROPYLENE GLYCOL MONOPHENYL ETHER PROPYLENE GLYCOL 1-MONOPHENYL ETHER PHENOXY PROPANOL AURORA KA-7000 DOWANOL(TM) PPH beta-phenoxyisopropanol -Phenoxy-2-propanol Phenyl-beta-hydroxypropyl ether Propylene phenoxetol propylenephenoxetol 1-PHENOXY-2-PROPANOL, 93+% (DOWANOL PPH) 1-Phenoxyisopropanol PROPYLENEPHENOXYTOL,REAGENT 2-PROPYLENEGLYCOL1-PHENYLETHER 1-Phenoxy-2-propan-2-ol 1-PHENOXY-2-PROPANOL: TECH., 85% 1-Phenoxy-2-pr DOWANOL(R) PPh, Propylene glycol phenyl ether, Propylene phenoxytol Propylene glycol phenyl ether, Propylene phenoxytol 1-Phenoxy-1-methylethanol 1-Methyl-2-phenoxyethanol 1-Phenoxypropane-2-ol 3-Phenoxypropane-2-ol 1-Phenoxy-2-propanol,97% 1-Phenoxy-2-propanol,85% Propanol, 1-phenoxy- 1-Phenoxy-2-propanol ,98% 1-Phenoxy-2-propanol,Propylene glycol phenyl ether, Propylene phenoxytol 1-Phenoxy-2-propanol,DOWANOL PPh, Propylene glycol phenyl ether, Propylene phenoxytol (2S)-1-phenoxy-2-propanol 1-Phenoxy-2-propanol, 99.5% 1-Phenoxy-2-propanol, 99.5%, for synthesis 1-Phenoxy-2-propanol> 1-Phenoxy-2-propanol 770-35-4 1-PHENOXYPROPAN-2-OL PROPYLENE GLYCOL PHENYL ETHER Phenoxyisopropanol C16045600 1-Phenoxy-2-propanol 770-35-4 C6H5OCH2CHOHCH3 C6H6C3H7O2 C9 to C30 Building Blocks Alcohols Organic Building Blocks Oxygen Compounds Benzhydrols, Benzyl & Special Alcohols