β-N-AcetylglucosaMinidase
- CAS No.
- 9012-33-3
- Chemical Name:
- β-N-AcetylglucosaMinidase
- Synonyms
- NAG;MPS3B;NAGLU;MPS-IIIB;EC 3.2.1.52;EC 3.2.1.30;β-N-acetylhexosaminidase;β-N-AcetylglucosaMinidase;β-N-AcetylglucosaMinidase;Acetylglucosaminidase, B2
- CBNumber:
- CB3451584
- Molecular Formula:
- NULL
- Molecular Weight:
- 0
- MDL Number:
- MFCD00081402
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H334 |
Precautionary statements | P261-P285-P304+P341-P342+P311-P501 |
Hazard Codes | B |
Risk Statements | 20/22-24-37/38-41-42 |
Safety Statements | 53-26-36/37/39-45 |
WGK Germany | 3 |
F | 10 |
β-N-AcetylglucosaMinidase price More Price(20)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | A2264 | β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean) ammonium sulfate suspension, ≥10?units/mg protein | 9012-33-3 | 5units | $165 | 2024-03-01 | Buy |
Sigma-Aldrich | A2264 | β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean) ammonium sulfate suspension, ≥10?units/mg protein | 9012-33-3 | 10units | $302 | 2024-03-01 | Buy |
Sigma-Aldrich | A6805 | β-N-Acetylglucosaminidase from Streptococcus pneumoniae recombinant, expressed in E. coli, buffered aqueous solution | 9012-33-3 | 1vial | $639 | 2024-03-01 | Buy |
Sigma-Aldrich | A2264 | β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean) ammonium sulfate suspension, ≥10?units/mg protein | 9012-33-3 | 25units | $566 | 2024-03-01 | Buy |
Sigma-Aldrich | 110116 | β1-2,3,4,6-N-Acetylglucosaminidase, | 9012-33-3 | 1u | $523 | 2024-03-01 | Buy |
β-N-AcetylglucosaMinidase Chemical Properties,Uses,Production
Uses
β -N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer’s Disease 1 . Acetylglucosaminidase from Canavalia ensiformis has been used to study enzymic detachment of biofilms.
Uses
Bovine kidney β-N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer′s Disease .
Flammability and Explosibility
Not classified
Biochem/physiol Actions
β-N-Acetylglucosaminidase from Streptococcus pneumoniae is an extracellular glycosidase and has broad specificity over the β1-3 and β1-6 linkages present in mucins. It belongs to the glycoside hydrolase family 85 (GH85). Also called endo-β-N-acetylglucosaminidase, it cleaves at the asparagine residue of the di-N-acetylchitobiose structure in oligosaccharides and acts on fucosylated N-glycan core. Its deglycosylation functionality is exploited in studying functions of glycoproteins.
Purification Methods
Purify it by chromatography on DEAD-Biogel, hydroxylapatite chromatography and gel filtration through Sephacryl S200. Two isoforms: a hexosaminidase EI with Km 177WM
β-N-AcetylglucosaMinidase Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30241 | 58 |
Wuhan Fortuna Chemical Co.,Ltd | +8618007136271 | hk@fortunachem.com | China | 5998 | 58 |
Watson Biotechnology Co.,Ltd | +86-18186686046 +86-18186686046 | sales01@watsonbiotech.cn | China | 5821 | 58 |
Shanghai Yingxin Laboratory Equipment Co., Ltd. | 021-021-59178156 17002132182 | 3146474380@qq.com | China | 11603 | 58 |
Shanghai Baoman Biotechnology Co., Ltd. | 021-62130998 | baomanbio@163.com | China | 108 | 55 |
GlycoSciTech Co. Ltd, Jinan, China | 18906399270 18906399270 | watergreen77@yahoo.com | China | 157 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9815 | 79 |
Shanghai BeiZhuo Biotech Co., Ltd. | 021-61119791,13386096464 | bzswkf@foxmail.com | China | 3921 | 50 |
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