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ChemicalBook >> CAS DataBase List >>Fulvestrant (ICI 182780) S enantiomer

Fulvestrant (ICI 182780) S enantiomer

CAS No.
1316849-17-8
Chemical Name:
Fulvestrant (ICI 182780) S enantiomer
Synonyms
ZD 9238 S enantiomer;ZM 182780 S enantiomer;ICI 182780 S enantiomer;Fulvestrant S enantiomer;Fulvestrant (ICI 182780) S enantiomer;Fulvestrant impurity 11/Fulvestrant S enantiomer;Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(S)-(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7α,17β)-;(1S,3aS,4R,9bS,11aS)-11a-methyl-4-[9-(4,4,5,5,5-p entafluoropentanesulfinyl)nonyl]-1H,2H,3H,3aH,3 bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phena nthrene-1,7-diol
CBNumber:
CB33386478
Molecular Formula:
C32H47F5O3S
Molecular Weight:
606.78
MDL Number:
MFCD31619291
MOL File:
1316849-17-8.mol
Last updated:2025-04-18 09:52:08

Fulvestrant (ICI 182780) S enantiomer Properties

Boiling point 674.8±55.0 °C(Predicted)
Density 1.201±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 10.27±0.70(Predicted)

Fulvestrant (ICI 182780) S enantiomer Chemical Properties,Uses,Production

Uses

Fulvestrant S enantiomer (ICI 182780 S enantiomer) is the S enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.

References

[1] Caprioglio D, et al. An alternative synthesis of the breast cancer drug fulvestrant (Faslodex?): catalyst control over C-C bond formation. Chem Commun (Camb). 2015;51(80):14866-14868. DOI:10.1039/c5cc05805h
[2] Wakeling AE, et al. A potent specific pure antiestrogen with clinical potential. Cancer Res. 1991;51(15):3867-3873. PMID:1855205

Fulvestrant (ICI 182780) S enantiomer Preparation Products And Raw materials

Raw materials

Preparation Products

Fulvestrant (ICI 182780) S enantiomer Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32265 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19103 58
Nanjing Shizhou Biology Technology Co.,Ltd 13675144456 sean.lv@synzest.com China 10784 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29774 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9835 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 233051 58
Adooq Bioscience LLC 400-025-6535 sales@adooq.cn China 18215 58

1316849-17-8(Fulvestrant (ICI 182780) S enantiomer)Related Search:

Fulvestrant (ICI 182780) S enantiomer Fulvestrant S enantiomer Fulvestrant impurity 11/Fulvestrant S enantiomer ICI 182780 S enantiomer ZD 9238 S enantiomer ZM 182780 S enantiomer Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(S)-(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7α,17β)- (1S,3aS,4R,9bS,11aS)-11a-methyl-4-[9-(4,4,5,5,5-p entafluoropentanesulfinyl)nonyl]-1H,2H,3H,3aH,3 bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phena nthrene-1,7-diol 1316849-17-8