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ChemicalBook >> CAS DataBase List >>3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide

3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide

CAS No.
1316059-00-3
Chemical Name:
3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide
Synonyms
159344;3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide;Benzenesulfonamide, 3-[[6-[(5-chloro-2-pyridinyl)amino]-4-pyrimidinyl]amino]-4-(ethylsulfonyl)-N-methyl-;3-({6-[(5-chloropyridin-2-yl)amino]pyrimidin-4-yl}amino)-4-(ethanesulfonyl)-N-methylbenzene-1-sulfonamide
CBNumber:
CB24868752
Molecular Formula:
C18H19ClN6O4S2
Molecular Weight:
482.96
MDL Number:
MFCD29919171
MOL File:
1316059-00-3.mol
Last updated:2024-11-06 15:28:16

3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide Properties

storage temp. Store at -20°C
solubility DMSO : 250 mg/mL (517.64 mM; Need ultrasonic)
form Solid
color Off-white to light yellow

3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide Chemical Properties,Uses,Production

Biological Activity

GSK854 is a potent Inhibitor of Troponin I-Interacting Kinase (TNNI3K). GSK854 is a suitable lead for identifying new cardiac medicines and have been employed as in vivo tools in investigational studies aimed at defining the role of TNNI3K within heart failure[1].

References

[1]. Philp J, et al. 4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase (TNNI3K) Inhibitors. J Med Chem. 2018;61(7):3076-3088.

3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32080 58
ChemShuttle, Inc. 0510-83588313-802 18800520310; sales@chemshuttle.com China 2996 62
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4512 55
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8011 62
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 Sales@ATKchemical.com China 7257 58
Shanghai Dongyang Biotechnology Co., Ltd. 0512-0512-13601744364 13601744364 chemsharker@126.com China 917 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 6813 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29977 58

View Lastest Price from 3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GSK854 pictures 2024-11-06 GSK854
1316059-00-3
 US $247.00-788.00 / mg 98.79% 10g TargetMol Chemicals Inc.
  • GSK854 pictures
  • GSK854
    1316059-00-3
  • US $247.00-788.00 / mg
  • 98.79%
  • TargetMol Chemicals Inc.
3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide 159344 Benzenesulfonamide, 3-[[6-[(5-chloro-2-pyridinyl)amino]-4-pyrimidinyl]amino]-4-(ethylsulfonyl)-N-methyl- 3-({6-[(5-chloropyridin-2-yl)amino]pyrimidin-4-yl}amino)-4-(ethanesulfonyl)-N-methylbenzene-1-sulfonamide 1316059-00-3 C18H19ClN6O4S2