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ChemicalBook >> CAS DataBase List >>PROTAC K-Ras Degrader-1

PROTAC K-Ras Degrader-1

CAS No.
2378258-52-5
Chemical Name:
PROTAC K-Ras Degrader-1
Synonyms
K-Ras Degrader-1;PROTAC K-Ras Degrader-1;2-Piperazineacetonitrile, 4-[2-[[(2S,4R)-4-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]-1-methyl-2-pyrrolidinyl]methoxy]-5,6,7,8-tetrahydro-7-(1-naphthalenyl)pyrido[3,4-d]pyrimidin-4-yl]-1-(1-oxo-2-propen-1-yl)-, (2S)-
CBNumber:
CB15540584
Molecular Formula:
C53H62N10O10
Molecular Weight:
999.14
MDL Number:
MFCD32263411
MOL File:
2378258-52-5.mol
Last updated:2024-07-02 08:55:01

PROTAC K-Ras Degrader-1 Properties

Density 1.40±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 33.33 mg/mL (33.36 mM)
pka 10.74±0.40(Predicted)
form Solid
color Light yellow to yellow

PROTAC K-Ras Degrader-1 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0106329 PROTACK-RasDegrader-1 98.05% 2378258-52-5 1mg $550 2021-12-16 Buy
ChemScene CS-0106329 PROTACK-RasDegrader-1 98.05% 2378258-52-5 5mg $1500 2021-12-16 Buy
ChemScene CS-0106329 PROTACK-RasDegrader-1 98.05% 2378258-52-5 10mg $2500 2021-12-16 Buy
Product number Packaging Price Buy
CS-0106329 1mg $550 Buy
CS-0106329 5mg $1500 Buy
CS-0106329 10mg $2500 Buy

PROTAC K-Ras Degrader-1 Chemical Properties,Uses,Production

Description

PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].

References

[1]. CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2.

PROTAC K-Ras Degrader-1 Preparation Products And Raw materials

Raw materials

Preparation Products

PROTAC K-Ras Degrader-1 Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32080 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1388 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11217 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10002 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822 czbjpharma@126.com China 18478 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 13417589054 trendseenbio@gmail.com China 9470 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 4870 58
PROTAC K-Ras Degrader-1 K-Ras Degrader-1 2-Piperazineacetonitrile, 4-[2-[[(2S,4R)-4-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]-1-methyl-2-pyrrolidinyl]methoxy]-5,6,7,8-tetrahydro-7-(1-naphthalenyl)pyrido[3,4-d]pyrimidin-4-yl]-1-(1-oxo-2-propen-1-yl)-, (2S)- 2378258-52-5