ChemicalBook >> CAS DataBase List >>PBOX-15
PBOX-15
- CAS No.
- 354759-10-7
- Chemical Name:
- PBOX-15
- Synonyms
- PBOX-15;PBOX15,PBOX 15;PBOX-15 >=98% (HPLC);Naphtho[2,3-b]pyrrolo[1,2-d][1,4]oxazepin-4-ol, 5-(1-naphthalenyl)-, 4-acetate
- CBNumber:
- CB14668333
- Molecular Formula:
- C28H19NO3
- Molecular Weight:
- 417.46
- MDL Number:
- MFCD31558509
- MOL File:
- 354759-10-7.mol
Last updated:2025-04-18 09:51:41
| FDA UNII | 687B9541N2 |
|---|
PBOX-15 Chemical Properties,Uses,Production
Uses
PBOX-15 is a microtubule targeting agent. PBOX-15 induces apoptosis by promoting tubulin depolymerization in tumor cells[1][2].
References
[1] Maginn EN, et al. PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells. Br J Cancer. 2011 Jan 18;104(2):281-9. DOI:10.1038/sj.bjc.6606035
[2] Mulligan JM, et al. Identification of tubulin as the molecular target of proapoptotic pyrrolo-1,5-benzoxazepines. Mol Pharmacol. 2006 Jul;70(1):60-70. DOI:10.1124/mol.105.021204
PBOX-15 Preparation Products And Raw materials
Raw materials
Preparation Products
PBOX-15 Suppliers
Global( 6)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19905 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1248 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19965 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | sales@biosynth.com | China | 233051 | 58 |
PBOX-15
Naphtho[2,3-b]pyrrolo[1,2-d][1,4]oxazepin-4-ol, 5-(1-naphthalenyl)-, 4-acetate
PBOX-15 >=98% (HPLC)
PBOX15,PBOX 15
354759-10-7