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ChemicalBook >> CAS DataBase List >>4(1H)-Quinazolinone, 2-[3-[(2,6-diMethylphenoxy)Methyl]-4-Methoxyphenyl]-2,3-dihydro-3-(3-pyridinylMethyl)-

4(1H)-Quinazolinone, 2-[3-[(2,6-diMethylphenoxy)Methyl]-4-Methoxyphenyl]-2,3-dihydro-3-(3-pyridinylMethyl)-

CAS No.
1338824-20-6
Chemical Name:
4(1H)-Quinazolinone, 2-[3-[(2,6-diMethylphenoxy)Methyl]-4-Methoxyphenyl]-2,3-dihydro-3-(3-pyridinylMethyl)-
Synonyms
NCGC00229600;2-[3-[(2,6-dimethylphenoxy)methyl]-4-methoxyphenyl]-3-(pyridin-3-ylmethyl)-1,2-dihydroquinazolin-4-one;2-(3-((2,6-Dimethylphenoxy)methyl)-4-methoxyphenyl)-3-(pyridin-3-ylmethyl)-2,3-dihydroquinazolin-4(1H)-one;4(1H)-Quinazolinone, 2-[3-[(2,6-diMethylphenoxy)Methyl]-4-Methoxyphenyl]-2,3-dihydro-3-(3-pyridinylMethyl)-;disease,cAMP,Inhibitor,Thyroid-stimulating hormone Receptor,NCGC00229600,fibroblasts,endogenously,Thyrotropin receptor,TSH Receptor,antibody,Graves,NCGC-00229600,inhibit,NCGC 00229600
CBNumber:
CB12668414
Molecular Formula:
C30H29N3O3
Molecular Weight:
479.56956
MDL Number:
MFCD25977097
MOL File:
1338824-20-6.mol
Last updated:2024-10-28 23:16:16

4(1H)-Quinazolinone, 2-[3-[(2,6-diMethylphenoxy)Methyl]-4-Methoxyphenyl]-2,3-dihydro-3-(3-pyridinylMethyl)- Properties

storage temp. Store at -20°C
solubility DMSO : 50 mg/mL (104.26 mM; Need ultrasonic)
form Solid
color White to off-white

4(1H)-Quinazolinone, 2-[3-[(2,6-diMethylphenoxy)Methyl]-4-Methoxyphenyl]-2,3-dihydro-3-(3-pyridinylMethyl)- Chemical Properties,Uses,Production

Biological Activity

NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves’ disease[1].

References

[1]. Neumann S, et al. A new small-molecule antagonist inhibits Graves’ disease antibody activation of the TSH receptor. J Clin Endocrinol Metab. 2011 Feb;96(2):548-54.

4(1H)-Quinazolinone, 2-[3-[(2,6-diMethylphenoxy)Methyl]-4-Methoxyphenyl]-2,3-dihydro-3-(3-pyridinylMethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

4(1H)-Quinazolinone, 2-[3-[(2,6-diMethylphenoxy)Methyl]-4-Methoxyphenyl]-2,3-dihydro-3-(3-pyridinylMethyl)- Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 31991 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38460 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 4422 55
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62163 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19699 58

View Lastest Price from 4(1H)-Quinazolinone, 2-[3-[(2,6-diMethylphenoxy)Methyl]-4-Methoxyphenyl]-2,3-dihydro-3-(3-pyridinylMethyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
NCGC00229600 pictures 2024-10-28 NCGC00229600
1338824-20-6
 US $58.00-223.00 / mg 99.27% 10g TargetMol Chemicals Inc.
NCGC00229600 pictures 2024-10-28 NCGC00229600
1338824-20-6
 US $58.00-223.00 / mg 99.27% 10g TargetMol Chemicals Inc.
  • NCGC00229600 pictures
  • NCGC00229600
    1338824-20-6
  • US $58.00-223.00 / mg
  • 99.27%
  • TargetMol Chemicals Inc.
  • NCGC00229600 pictures
  • NCGC00229600
    1338824-20-6
  • US $58.00-223.00 / mg
  • 99.27%
  • TargetMol Chemicals Inc.

4(1H)-Quinazolinone, 2-[3-[(2,6-diMethylphenoxy)Methyl]-4-Methoxyphenyl]-2,3-dihydro-3-(3-pyridinylMethyl)- Spectrum

4(1H)-Quinazolinone, 2-[3-[(2,6-diMethylphenoxy)Methyl]-4-Methoxyphenyl]-2,3-dihydro-3-(3-pyridinylMethyl)- 2-[3-[(2,6-dimethylphenoxy)methyl]-4-methoxyphenyl]-3-(pyridin-3-ylmethyl)-1,2-dihydroquinazolin-4-one NCGC00229600 disease,cAMP,Inhibitor,Thyroid-stimulating hormone Receptor,NCGC00229600,fibroblasts,endogenously,Thyrotropin receptor,TSH Receptor,antibody,Graves,NCGC-00229600,inhibit,NCGC 00229600 2-(3-((2,6-Dimethylphenoxy)methyl)-4-methoxyphenyl)-3-(pyridin-3-ylmethyl)-2,3-dihydroquinazolin-4(1H)-one 1338824-20-6