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INDEX NAME NOT YET ASSIGNED
- CAS No.
- 2719679-31-7
- Chemical Name:
- INDEX NAME NOT YET ASSIGNED
- Synonyms
- (±)-MMT5-14
- CBNumber:
- CB112220749
- Molecular Formula:
- C39H55N6O8P
- Molecular Weight:
- 766.86
- MDL Number:
- MOL File:
- 2719679-31-7.mol
Last updated:2023-07-12 17:15:31
INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production
Biological Activity
(±)-MMT5-14 is a derivative of remdesivir with antiviral activity.1 It increases the viability of Vero E6 cells infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; EC50 = 0.4 μM), as well as Vero E6 cells infected with the Alpha, Beta, Gamma, or Delta SARS-CoV-2 variants (EC50s = 2.5, 15.9, 1.7, and 5.6 μM, respectively). (±)-MMT5-14 exhibits increased plasma and lung concentrations compared with remdesivir in hamsters when administered at a dose of 10 mg/kg.
References
1.Hu, H., Traore, M.D.M., Li, R., et al.Optimization of the prodrug moiety of remdesivir to improve lung exposure/selectivity and enhance anti-SARS-CoV-2 activityJ. Med. Chem.65(18)12044-12054(2022)
INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials
Raw materials
Preparation Products
INDEX NAME NOT YET ASSIGNED Suppliers
Global( 4)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11974 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19699 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
(±)-MMT5-14
2719679-31-7
C39H55N6O8P