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ChemicalBook >> CAS DataBase List >>DS-88790512)

DS-88790512)

CAS No.
2231089-95-3
Chemical Name:
DS-88790512)
Synonyms
DS-88790512);DS88790512 (DS 88790512;DS88790512 hydrochloride (DS 88790512;Benzonitrile, 4-[[(1R,2R,3aR,7aS)-2-[(3R)-3-amino-1-piperidinyl]octahydro-7a-methyl-5-oxo-1H-inden-1-yl]oxy]-
CBNumber:
CB04844734
Molecular Formula:
C22H29N3O2
Molecular Weight:
367.48
MDL Number:
MFCD31813668
MOL File:
2231089-95-3.mol
Last updated:2025-04-18 09:51:29

DS-88790512) Properties

Boiling point 540.6±50.0 °C(Predicted)
Density 1.20±0.1 g/cm3(Predicted)
pka 10.98±0.20(Predicted)

DS-88790512) Chemical Properties,Uses,Production

Uses

DS88790512 is a potent, selective, and orally bioavailable TRPC6 inhibitor with an IC50 of 11 nM.

References

[1] Motoyama K, et al. Discovery of a bicyclo[4.3.0]nonane derivative DS88790512 as a potent, selective, and orally bioavailable blocker of transient receptor potential canonical 6 (TRPC6). Bioorg Med Chem Lett. 2018 Jul 1;28(12):2222-2227. DOI:10.1016/j.bmcl.2018.03.056

DS-88790512) Preparation Products And Raw materials

Raw materials

Preparation Products

DS-88790512) Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32265 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9729 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29774 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19930 58
Adooq Bioscience LLC 400-025-6535 sales@adooq.cn China 18215 58
DS88790512 hydrochloride (DS 88790512 DS-88790512) DS88790512 (DS 88790512 Benzonitrile, 4-[[(1R,2R,3aR,7aS)-2-[(3R)-3-amino-1-piperidinyl]octahydro-7a-methyl-5-oxo-1H-inden-1-yl]oxy]- 2231089-95-3