ChemicalBook >> CAS DataBase List >>Ropivacaine hydrochloride
Ropivacaine hydrochloride
- CAS No.
- 132112-35-7
- Chemical Name:
- Ropivacaine hydrochloride
- Synonyms
- ROPIVACAINE HCL;ROPIVACAINE HYDROCHLORIDE MONOHYDRATE;Ropivacaine hydrochloride hydrate;LEA-103;LEA-103 HCl;Ropivacaine HCI;S-ROPIVACAINE HCL;Ropivacaine HCl.H2O;Ropivacaine HCl (mono);Ropivacaine HCl hydrate
- CBNumber:
- CB0369811
- Molecular Formula:
- C17H26N2O.ClH.H2O
- Molecular Weight:
- 328.88
- MDL Number:
- MFCD02102164
- MOL File:
- 132112-35-7.mol
- MSDS File:
- SDS
Last updated:2024-11-14 14:09:35
| Melting point | 267-269°C |
|---|---|
| alpha | D20 -7.28° (c = 2 in water) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble5mg/mL, clear |
| form | powder |
| color | white to off-white |
| optical activity | [α]/D -9 to -12, c = 1 in methanol |
| InChIKey | VSHFRHVKMYGBJL-CKUXDGONSA-N |
| CAS DataBase Reference | 132112-35-7(CAS DataBase Reference) |
| NCI Dictionary of Cancer Terms | ropivacaine hydrochloride |
| FDA UNII | V910P86109 |
| NCI Drug Dictionary | ropivacaine hydrochloride |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H318 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | T,Xi |
| Risk Statements | 26/27/28-41 |
| Safety Statements | 22-36/37/39-45-39-26 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| HS Code | 2933399090 |
Ropivacaine hydrochloride price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R0283 | Ropivacaine hydrochloride monohydrate ≥98% (HPLC) | 132112-35-7 | 10mg | $84.1 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR2303 | Ropivacaine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 132112-35-7 | 500MG | $253 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1605500 | Ropivacaine hydrochloride United States Pharmacopeia (USP) Reference Standard | 132112-35-7 | 200mg | $436 | 2024-03-01 | Buy |
| Cayman Chemical | 21422 | Ropivacaine (hydrochloride hydrate) ≥98% | 132112-35-7 | 25mg | $63 | 2024-03-01 | Buy |
| Cayman Chemical | 21422 | Ropivacaine (hydrochloride hydrate) ≥98% | 132112-35-7 | 50mg | $117 | 2024-03-01 | Buy |
Ropivacaine hydrochloride Chemical Properties,Uses,Production
Description
(–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve. (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine . Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.
Chemical Properties
White Solid
Uses
Ropivacaine hydrochloride monohydrate has been used as an analyte in tandem mass spectrometry and as an amide-based local anaesthetic to test its effect on breast cancer cell methylation.
Uses
Anesthetic (local).
Definition
ChEBI: The monohydrate form of (S)-ropivacaine hydrochloride.
General Description
Ropivacaine has lidocaine-related structure with tertiary amine side chains.?It is a pure S(-)enantiomer with a propyl group on the piperidine nitrogen atom.
Biochem/physiol Actions
Local anaesthetic with less cardiotoxicity than bupivacaine; causes reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the cell membrane of the nerve fibers.
Ropivacaine hydrochloride Preparation Products And Raw materials
Global( 394)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1001 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12835 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
| Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 427 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 | sales@sdperfect.com | China | 294 | 58 |
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1085 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Wuhan Ruichi Technology Co., Ltd | +8613545065237 | admin@whrchem.com | China | 153 | 58 |
| Shaanxi Franta Biotechnology Co., Ltd | +86-13082019107 +86-13082019107 | admin@flanderff.com | China | 206 | 58 |
| Apeloa production Co.,Limited | +8619933239880 | admin@apcl.com.cn | China | 852 | 58 |
View Lastest Price from Ropivacaine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-14 | Ropivacaine hydrochloride monohydrate
132112-35-7
|
US $32.00-72.00 / mg | 99.80% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-14 | Ropivacaine hydrochloride
132112-35-7
|
US $0.00-0.00 / Kg/Drum | 1KG | 99%-101%;EP | 500KGS | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-11 | Ropivacaine hydrochloride
132112-35-7
|
US $20.00 / kg | 1kg | 99% | 10000 | Hebei Miaoyin Technology Co.,Ltd |
-
- Ropivacaine hydrochloride monohydrate
132112-35-7
- US $32.00-72.00 / mg
- 99.80%
- TargetMol Chemicals Inc.
-
- Ropivacaine hydrochloride
132112-35-7
- US $0.00-0.00 / Kg/Drum
- 99%-101%;EP
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Ropivacaine hydrochloride
132112-35-7
- US $20.00 / kg
- 99%
- Hebei Miaoyin Technology Co.,Ltd
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IP/USP/BP/EP
132112-35-7
13112-35-7
CAS NO.98717-15
132115-35-7
C17H26N2OxHCL
C17H26N2OHCl
C17H26N2OHCLH2O
C17H28N2O2HCl
C17H26N2O2HClH2O
C17H26N2OClHH2O
Inhibitors
Chiral Reagents
Intermediates & Fine Chemicals
Pharmaceuticals
API
132112-35-7