ChemicalBook >> CAS DataBase List >>9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)nonanoic acid
9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)nonanoic acid
- CAS No.
- 2682112-09-8
- Chemical Name:
- 9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)nonanoic acid
- Synonyms
- Thalidomide-5-NH-C8-COOH;9-[[2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]amino]nonanoic Acid;9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)nonanoic acid
- CBNumber:
- CB011915843
- Molecular Formula:
- C22H27N3O6
- Molecular Weight:
- 429.47
- MDL Number:
- MOL File:
- 2682112-09-8.mol
Last updated:2025-04-17 18:22:24
9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)nonanoic acid Chemical Properties,Uses,Production
Uses
Pomalidomide-5'-C8-acid (Compound 3d') is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide-5'-C8-acid can be used in the synthesis of PROTACs[1].
References
[1] Rao, Yu, et al. Preparation of isoindoline derivatives as degradation agent targeting both BTK and GSPT1 proteins and its application. Patent. CN115304606
9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)nonanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)nonanoic acid
Thalidomide-5-NH-C8-COOH
9-[[2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]amino]nonanoic Acid
2682112-09-8