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ChemicalBook >> CAS DataBase List >>(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane

CAS No.
156474-22-5
Chemical Name:
(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane
Synonyms
Atazanavir Impurity 32;(2S,3R)-1,2-Epoxy-(Boc amino)-4-phenylbutane;(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane;threo-N-(Tert-Butoxy)Carbonyl D-phenylalanine epoxide;tert-butyl ((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbaMate;(2S,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane;tert-butyl [(2R,3S)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate;(2S,3R)-3-(tert-ButoxycarbonylaMino)-1,2-epoxy-4-phenylbutane;tert-butyl N-[(1R)-1-[(2S)-oxiran-2-yl]-2-phenylethyl]carbamate;2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate
CBNumber:
CB01122327
Molecular Formula:
C15H21NO3
Molecular Weight:
263.33
MDL Number:
MFCD08061626
MOL File:
156474-22-5.mol
Last updated:2023-07-22 08:27:56

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Properties

Melting point 90-95°C
Boiling point 398.8±25.0 °C(Predicted)
Density 1.118±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform, DMSO, Methanol
form Solid
pka 12.19±0.46(Predicted)
color White

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation CHM0068781 (2S,3R)-3-(N-BOC-AMINO)-1-OXIRANE-4-PHENYLBUTANE 95.00% 156474-22-5 5MG $502.81 2021-12-16 Buy
JR MediChem JR6-L2705 Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester 96% 156474-22-5 1g $980 2021-12-16 Buy
JR MediChem JR6-L2705 Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester 96% 156474-22-5 5g $2480 2021-12-16 Buy
JR MediChem JR6-L2705 Carbamicacid,N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-,1,1-dimethylethylester 96% 156474-22-5 25g $7980 2021-12-16 Buy
Ambeed A789622 tert-Butyl((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbamate 97% 156474-22-5 1g $43 2021-12-16 Buy
Product number Packaging Price Buy
CHM0068781 5MG $502.81 Buy
JR6-L2705 1g $980 Buy
JR6-L2705 5g $2480 Buy
JR6-L2705 25g $7980 Buy
A789622 1g $43 Buy

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Chemical Properties,Uses,Production

Uses

(2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane is an intermediate in the synthesis of Atazanavir (A790050), a novel azapeptide HIV protease inhibitor used as an antiviral agent.

244092-76-0
156474-22-5
Synthesis of (2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane from 3R enantiomer

(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 60)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd.
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Neostar United (Changzhou) Industrial Co., Ltd.
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BOC Sciences
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Nextpeptide Inc
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Hangzhou Proserre Chemical Co.,Ltd.
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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ShenZhen Trendseen Biological Technology Co.,Ltd.
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China National Standard Pharmaceutical Corporation Limited
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LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43340 58
Suzhou ARTK Medchem Co., Ltd.
+86-512-68323658 +86-18168183658 sales1@artkmedchem.com China 39004 58
(2S,3R)-3-(N-Boc-amino)-1-oxirane-4-phenylbutane (2S,3R)-3-(tert-ButoxycarbonylaMino)-1,2-epoxy-4-phenylbutane tert-butyl ((R)-1-((S)-oxiran-2-yl)-2-phenylethyl)carbaMate 2-Methyl-2-propanyl {(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl}carba mate threo-N-(Tert-Butoxy)Carbonyl D-phenylalanine epoxide (2S,3R)-3-[(t-Butoxycarbonyl)amino]-4-phenyl-1,2-epoxybutane Atazanavir Impurity 32 tert-butyl N-[(1R)-1-[(2S)-oxiran-2-yl]-2-phenylethyl]carbamate tert-butyl [(2R,3S)]-(-)-(1-oxiranyl-2-phenylethyl)carbamate (2S,3R)-1,2-Epoxy-(Boc amino)-4-phenylbutane Carbamic acid, N-[(1R)-1-[(2S)-2-oxiranyl]-2-phenylethyl]-, 1,1-dimethylethyl ester Atazanavir Intermediate Enantiomer ((2S,3R)-3-(tert-Butoxycarbonylamino)-1,2-epoxy-4-phenylbutane) 156474-22-5 Aromatics, Chiral Reagents, Heterocycles