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ChemicalBook >> CAS DataBase List >>2-Thiopheneacetamide, 4-bromo-N-[4-[[6-methyl-2-(1-pyrrolidinyl)-4-pyrimidinyl]amino]phenyl]-

2-Thiopheneacetamide, 4-bromo-N-[4-[[6-methyl-2-(1-pyrrolidinyl)-4-pyrimidinyl]amino]phenyl]-

CAS No.
2716890-91-2
Chemical Name:
2-Thiopheneacetamide, 4-bromo-N-[4-[[6-methyl-2-(1-pyrrolidinyl)-4-pyrimidinyl]amino]phenyl]-
Synonyms
2-Thiopheneacetamide, 4-bromo-N-[4-[[6-methyl-2-(1-pyrrolidinyl)-4-pyrimidinyl]amino]phenyl]-
CBNumber:
CB010790834
Molecular Formula:
C21H22BrN5OS
Molecular Weight:
472.4
MDL Number:
MOL File:
2716890-91-2.mol
Last updated:2024-11-16 15:32:52

2-Thiopheneacetamide, 4-bromo-N-[4-[[6-methyl-2-(1-pyrrolidinyl)-4-pyrimidinyl]amino]phenyl]- Properties

Density 1.513±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (211.69 mM; Need ultrasonic)
pka 13.34±0.70(Predicted)
form Solid
color Off-white to gray

2-Thiopheneacetamide, 4-bromo-N-[4-[[6-methyl-2-(1-pyrrolidinyl)-4-pyrimidinyl]amino]phenyl]- Chemical Properties,Uses,Production

Biological Activity

CHD1Li 6.11 is a potent oncogenic CHD1L inhibitor (IC50=3.3 μM for cat-CHD1L recombinant protein). CHD1Li 6.11 is an orally bioavailable antitumor agent, significantly reducing the tumor volume of CRC xenografts generated from isolated quasi mesenchymal cells (M-phenotype), which possess enhanced tumorigenic properties[1].

References

[1]. Prigaro BJ, et al. Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L. J Med Chem. 2022;65(5):3943-3961.

2-Thiopheneacetamide, 4-bromo-N-[4-[[6-methyl-2-(1-pyrrolidinyl)-4-pyrimidinyl]amino]phenyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Thiopheneacetamide, 4-bromo-N-[4-[[6-methyl-2-(1-pyrrolidinyl)-4-pyrimidinyl]amino]phenyl]- Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32080 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3135 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 Sales@ATKchemical.com China 7257 58
Shanghai Dongyang Biotechnology Co., Ltd. 0512-0512-13601744364 13601744364 chemsharker@126.com China 917 58
Nantong Hi-Future Biotechnology Co., Ltd 18051384581 sales@chemhifuture.com China 3056 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2561 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 6813 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58

View Lastest Price from 2-Thiopheneacetamide, 4-bromo-N-[4-[[6-methyl-2-(1-pyrrolidinyl)-4-pyrimidinyl]amino]phenyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CHD1Li 6.11 pictures 2024-11-16 CHD1Li 6.11
2716890-91-2
 US $93.00-372.00 / mg 98.03% 10g TargetMol Chemicals Inc.
  • CHD1Li 6.11 pictures
  • CHD1Li 6.11
    2716890-91-2
  • US $93.00-372.00 / mg
  • 98.03%
  • TargetMol Chemicals Inc.
2-Thiopheneacetamide, 4-bromo-N-[4-[[6-methyl-2-(1-pyrrolidinyl)-4-pyrimidinyl]amino]phenyl]- 2716890-91-2