Sclareol NEW
| Price | $38 | $53 | $74 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Sclareol | CAS No.: 515-03-7 |
| Purity: 99.58% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Sclareol |
| Description | Sclareol, a labdane-type diterpene isolated from clary sage (Salvia sclarea), exerts growth inhibition and cytotoxic activity against a variety of human Y cell lines. |
| In vitro | Ingestion of Sclareol in rats demonstrates an LD50 greater than 5 g/kg. |
| In vivo | Sclareol inhibits DNA synthesis in human breast cancer cell lines, inducing apoptosis that does not depend on p53 and causing cell cycle arrest at the G(0/1) phase. Intratumoral injection of Sclareol decreases in-vivo growth of breast cancer tumors. It demonstrates growth inhibition and cytotoxicity across various human cancer cell lines. Additionally, Sclareol exhibits anti-inflammatory activity in lipopolysaccharide-stimulated macrophages by reducing the expression of inflammatory cytokines and increasing the activity of antioxidant enzymes. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : < 1 mg/mL (insoluble or slightly soluble) DMSO : 45 mg/mL (145.87 mM) Ethanol : 23 mg/mL (74.6 mM) |
| Keywords | P-388 | inhibit | Salvia sclarea | human epidermal?carcinoma? | Inhibitor | Sclareol | leukemia | cell | Apoptosis |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Acetylcysteine | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin |
| Related Compound Libraries | Terpene Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Anti-Aging Compound Library | Bioactive Compounds Library Max | Ancient Chinese Classical Formulas Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36?Washington?Street, Wellesley?Hills
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