L-803,087 TRIFLUOROACETATE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Somatostatin receptors are often overexpressed in tumours and are potential therapeutic targets. Somatostatin receptor agonists can be used to study signaling pathways related somatostatin receptor. L 803087 is a somatostatin sst4 receptor agonist.
Biologische Aktivit?t
Potent and selective somatostatin sst 4 receptor agonist. K i values are 0.7, 199, 4720, 1280 and 3880 nM for cloned human sst 4 , sst 1 , sst 2 , sst 3 and sst 5 receptors respectively. Facilitates AMPA-mediated hippocampal synaptic responses in vitro and increases kainate-induced seizures in mice in vivo .
L-803,087 TRIFLUOROACETATE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte