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SUCCINYLCHOLINE

SUCCINYLCHOLINE Struktur
CAS-Nr.
Englisch Name:
SUCCINYLCHOLINE
Synonyma:
CBNumber:
CB6409041
Summenformel:
C14H30N2O4+2
Molgewicht:
290.4
MOL-Datei:
Mol file

SUCCINYLCHOLINE Eigenschaften

Sicherheit

SUCCINYLCHOLINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Biologische Funktion

Succinylcholine is given systemically because the molecule is charged and does not easily cross membranes. It is rapidly hydrolyzed by plasma cholinesterase to succinylmonocholine, which is pharmacologically inactive. Because plasma cholinesterase is synthesized in the liver, neuromuscular block may be prolonged in patients with liver disease. About 10% of succinylcholine is excreted unchanged in the urine. The response to succinylcholine may also be prolonged in individuals with a genetic defect leading to atypical plasma cholinesterase (homozygous incidence of about 1 in 2,500). In this case, the enzyme has a decreased affinity for substrates such as succinylcholine that can be measured by the dibucaine test.

SUCCINYLCHOLINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


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