5,6-Diamino-1,3-dimethylpyrimidin-2,4(1H,3H)-dion
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- CAS-Nr.
- 5440-00-6
- Bezeichnung:
- 5,6-Diamino-1,3-dimethylpyrimidin-2,4(1H,3H)-dion
- Englisch Name:
- 5,6-Diamino-1,3-dimethyluracil hydrate
- Synonyma:
- 5,6-DIAMINO-1,3-DIMETHYLPYRIMIDINE-2,4(1H,3H)-DIONE;NSC 15493;2,4(1H,3H);Doxofylline Impurity 19;Theophylline Impurities 1;5,6-Diamino-1,3-dimethylurea;4,5-DIAMINO-1,3-DIMETHYLURACIL;1,3-DIMETHYL-5,6-DIAMINOURACIL;5,6-DIAMINO-1,3-DIMETHYL URACIL;Uracil, 5,6-diamino-1,3-dimethyl-
- CBNumber:
- CB6155708
- Summenformel:
- C6H10N4O2
- Molgewicht:
- 170.17
- MOL-Datei:
- 5440-00-6.mol
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5,6-Diamino-1,3-dimethylpyrimidin-2,4(1H,3H)-dion Eigenschaften
- Schmelzpunkt:
- 210-214 °C (dec.)(lit.)
- Siedepunkt:
- 243.6±50.0℃ (760 Torr)
- Dichte
- 1.350±0.06 g/cm3 (20 ºC 760 Torr)
- Flammpunkt:
- 101.1±30.1℃
- L?slichkeit
- DMSO, Methanol
- Aggregatzustand
- Solid
- pka
- 4.42±0.70(Predicted)
- Farbe
- Pale Brown
- BRN
- 157451
- EPA chemische Informationen
- 2,4(1H,3H)-Pyrimidinedione, 5,6-diamino-1,3-dimethyl- (5440-00-6)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
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5,6-Diamino-1,3-dimethylpyrimidin-2,4(1H,3H)-dion Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Pale Brown Solid
Verwenden
5,6-Diamino-1,3-dimethyluracil hydrate can be used as reactant involved in the synthesis of biologically active molecules including: 1H-Imidazol-1-yl substituted 8-phenylxanthines for use as adenosine receptor ligands ; Pyrimidinyl purinediones via cyclocondensation ; Theophylline derivatives as adenosine receptor antagonists ; Pteridine analogs for use as monoamine oxidase B and nitric oxide synthase inhibitors ; Fused tricyclic xanthines and Cadmium uraciliminoethylpyridine complexes for use as antiproliferatives against C6 glioma cells6.
l?uterung methode
It recrystallises from EtOH. The hydrochloride has m 310o (from MeOH), and the perchlorate has m 246-248o. [UV: Bredereck et al. Chem Ber 92 583 1959, Taylor et al. J Am Chem Soc 77 2243 1955, Beilstein 25 III/IV 4133.]
5,6-Diamino-1,3-dimethylpyrimidin-2,4(1H,3H)-dion Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3,9-Dihydro-1,3,9-trimethyl-1H-purin-2,6-dion
8-(3-Pyridyl)theophyline
2,4(1H,3H)-Pteridinedione, 1,3-dimethyl-7-phenyl-
4,6-Dimethyl-1H-1,2,3-triazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione
NSC14355
5,6-Diamino-1,3-dimethylpyrimidin-2,4(1H,3H)-dion Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 113)Lieferanten
5440-00-6(5,6-Diamino-1,3-dimethylpyrimidin-2,4(1H,3H)-dion)Verwandte Suche:
Dihydro-6-imino-1,3-dimethyluracil
Cytosin-5-carbonsure
Dihydro-6-imino-1,3-dimethyl-3H-pyrimidin-2,4,5-trion-5-oxim
2,4-Dihydroxypyrimidin-5-carbonsure
5,6-Diamino-1,3-dimethylpyrimidin-2,4(1H,3H)-dion
Uracil
1,3-Dimethyluracil
1,3-Dimethylharnstoff
7,9-Dihydro-1,3-dimethyl-1H-purin-2,6,8(3H)-trion
6-Amino-1,3-dimethyl-5-nitrosouracil
7,9-Dihydro-1,3,7-trimethyl-1H-purin-2,6,8(3H)-trion
6-Amino-1-isobutyl-3-methyl-5-nitrosouracil
- 1,3-Dimethyl-5,6-diamino-1,2,3,4-tetrahydropyrimidine-2,4-dione
- 1,3-Dimethyl-5,6-diaminopyrimidine-2,4(1H,3H)-dione
- 5,6-bis(azanyl)-1,3-dimethyl-pyrimidine-2,4-dione
- 5,6-diamino-1,3-dimethylpyrimidine-2,4-dione
- 5,6-diamino-1,3-dimethyl-pyrimidine-2,4-quinone
- 4,5-Diamino-1,3-dimethyl-2,6-dioxotetrahydropyrimidine
- NSC 15493
- 5,6-Diamino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione
- Uracil, 5,6-diamino-1,3-dimethyl-
- 4,5-DIAMINO-1,3-DIMETHYLURACIL
- 5,6-DIAMINO-1,3-DIMETHYL URACIL
- 4,5-DiaMino-1,3-diMethylpyriMidine-2,6-dione
- 1,3-DIMETHYL-5,6-DIAMINOURACIL
- 2,4(1H,3H)-Pyrimidinedione, 5,6-diamino-1,3-dimethyl-
- 5,6-DiaMino-1,3-diMethyluracil hydrate technical grade
- 5,6-Diamino-1,3-dimethylurea
- 2,4(1H,3H)
- 5,6-DIAMINO-1,3-DIMETHYLURACIL HYDRATE
- 3h)-pyrimidinedione,5,6-diamino-1,3-dimethyl-4(1h
- 5,6-diamino-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
- 5,6-Diamino-1,3-dimethyluracil (theophylline impurity)
- Doxofylline Impurity 19
- Theophylline Impurities 1
- 5,6-DIAMINO-1,3-DIMETHYLPYRIMIDINE-2,4(1H,3H)-DIONE
- 5,6-Diamino-1,3-dimethyluracil 1-hydrate
- 5440-00-6
- C6H10N4O2H2O
- C6H10N4O2xH2O
- Heterocyclic Building Blocks
- Pyrimidines
- Building Blocks
- Nucleotides and Nucleosides
- 5-FOA
- Bases & Related Reagents
- Nucleotides
- Building Blocks
- C6 to C8
- Chemical Synthesis
- Heterocyclic Building Blocks
- Pyrimidines
