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McMMAE

McMMAE Struktur
863971-24-8
CAS-Nr.
863971-24-8
Englisch Name:
McMMAE
Synonyma:
McMMAE;Mc-MMAE;Mc MMAE;Maleimidocaproyl-monomethylauristatin E;37: PN: WO2007140371 PAGE: 273 claimed sequence;Mc-MMAE,Inhibitor,Drug-Linker Conjugates for ADC,McMMAE,Microtubule/Tubulin,Mc MMAE,inhibit;L-Valinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-;6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-[(1S)-1-{[(1S)-1-{[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-2-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl](methyl)carbamoyl}-2-methylpropyl]carbamoyl}-2-methylpropyl]-N-methylhexanamide;6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((S)-1-(((S)-1-(((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)(methyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)-N-methylhexanamide
CBNumber:
CB52668694
Summenformel:
C49H78N6O10
Molgewicht:
911.18
MOL-Datei:
863971-24-8.mol

McMMAE Eigenschaften

Siedepunkt:
1025.2±65.0 °C(Predicted)
Dichte
1.144±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C,unstable in solution, ready to use.
L?slichkeit
DMSO: ≥ 51 mg/mL (55.97 mM)
pka
13.63±0.46(Predicted)
Aggregatzustand
Powder
Farbe
White to light yellow

Sicherheit

McMMAE Chemische Eigenschaften,Einsatz,Produktion Methoden

McMMAE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


McMMAE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 75)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hangzhou Benoy Chemical Co., Ltd
+8617342059697
sales@benoychem.com China 315 58
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714
fandachem@gmail.com China 9220 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32820 60
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5906 58
BOC Sciences
+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Jurong Coupling Biotechnology Co., Ltd.
13656108824
coupling278191416@hotmail.com CHINA 184 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29815 58
Shaanxi Dideu Medichem Co. Ltd
18192627656
1012@dideu.com China 3002 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196
sale04@alfachem.cn China 13486 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32024 58

  • Mc MMAE
  • McMMAE
  • Mc-MMAE
  • 37: PN: WO2007140371 PAGE: 273 claimed sequence
  • Maleimidocaproyl-monomethylauristatin E
  • L-Valinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-
  • Mc-MMAE,Inhibitor,Drug-Linker Conjugates for ADC,McMMAE,Microtubule/Tubulin,Mc MMAE,inhibit
  • 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((S)-1-(((S)-1-(((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)(methyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)-N-methylhexanamide
  • 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-[(1S)-1-{[(1S)-1-{[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-2-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl](methyl)carbamoyl}-2-methylpropyl]carbamoyl}-2-methylpropyl]-N-methylhexanamide
  • 863971-24-8
  • C49H78N6O10
  • ADCs
  • ADC LINKER
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