MONOSIALOGANGLIOSIDE GM3 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Monosialoganglioside GM3 can have anti-tumor effects by regulating cell apoptosis, angiogenesis. Monosialoganglioside GM3 can also regulate peripheral insulin receptor signaling and increases in GM3 in adipose tissue of obese humans may contribute to insulin resistance.
Allgemeine Beschreibung
Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum. They contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage. For classification of gangliosides see Svennerholm, L., et al. (eds.),
Structure and Function of Gangliosides, New York, Plenum, 1980.
Biochem/physiol Actions
Monosialoganglioside GM3 has a potential role in cancer development and progression. Increased expression of GM3 has been observed in various types of cancer. Hence, it is used as a tumor-associated carbohydrate antigen during cancer vaccine development.
MONOSIALOGANGLIOSIDE GM3 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte