LEUPEPTIN TRIFLUOROACETATE SALT
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- CAS-Nr.
- 147385-61-3
- Englisch Name:
- LEUPEPTIN TRIFLUOROACETATE SALT
- Synonyma:
- LEUPEPTIN TRIFLUOROACETATE SALT;leupeptintrifluoroacetatesalt90+%;ACETYL-LEU-LEU-ARG-AL TRIFLUOROACETATE SALT;LEUPEPTIN TRIFLUOROACETATE FROM*MICROBIA L SOURCE;Leupeptin trifluoroacetate salt >=90% (HPLC), microbial;Leupeptin trifluoroacetate salt,Acetyl-Leu-Leu-Arg-al trifluoroacetate salt;2-acetamido-N-[1-[[5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide,2,2,2-trifluoroaceticaci
- CBNumber:
- CB1194874
- Summenformel:
- C22H39F3N6O6
- Molgewicht:
- 540.58
- MOL-Datei:
- 147385-61-3.mol
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LEUPEPTIN TRIFLUOROACETATE SALT Eigenschaften
- storage temp.
- -20°C
- L?slichkeit
- H2O: 10 mM Solutions are stable only a few hours. Stock solutions are stable up to 6 months at −20°C.
- Aggregatzustand
- powder
- Biologische Quelle
- microbial
- Wasserl?slichkeit
- H2O: 10mM (Solutions are stable only a few hours. Stock solutions are stable up to 6 months at -20 °C.)
LEUPEPTIN TRIFLUOROACETATE SALT Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Verwenden
Leupeptin Trifluoroacetate is a protease inhibitor, used in the characterization of macroautophagic flux in vivo using leupeptin-based assay.
Biochem/physiol Actions
Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. Effective concentration 10-100 μM. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.)
LEUPEPTIN TRIFLUOROACETATE SALT Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
LEUPEPTIN TRIFLUOROACETATE SALT Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 24)Lieferanten
147385-61-3()Verwandte Suche:
- LEUPEPTIN TRIFLUOROACETATE SALT
- ACETYL-LEU-LEU-ARG-AL TRIFLUOROACETATE SALT
- LEUPEPTIN TRIFLUOROACETATE FROM*MICROBIA L SOURCE
- leupeptintrifluoroacetatesalt90+%
- Leupeptin trifluoroacetate salt,Acetyl-Leu-Leu-Arg-al trifluoroacetate salt
- Leupeptin trifluoroacetate salt >=90% (HPLC), microbial
- 2-acetamido-N-[1-[[5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide,2,2,2-trifluoroaceticaci
- 147385-61-3
- C19H38N6O4C2HF3O2
- C20H38N6O4C2HF3O2
- Trypsin Inhibitors
- Enzymes, Inhibitors, and Substrates
- Analytical Enzymes
- BioChemical
- Biochemicals and Reagents
- A to C
- alpha
- Apoptosis Enzymes
- Application Index
- Calpain II
- Calpain II Inhibitors
- Cathepsin B
- Cathepsin H
- Cathepsin/Granzyme Inhibitors &
- Cell Signaling Enzymes
- Coagulation Proteins and Reagents
- D to K
- Endoproteinase Lys-C
- General Inhibitors
- Kallikrein tissue
- Aldehydes
- and Substrates
- Bioactive Small Molecules
- Biochemicals and Reagents
- Building Blocks
- C13-C60
- Calpain
- Carbonyl Compounds
- Cell Biology
- Cell Signaling and Neuroscience
- Chemical Synthesis
- Chymotrypsin
- Core Bioreagents
- Enzyme Inhibitors
- Enzyme Inhibitors by Enzyme
- Enzymes
- Inhibitors
- L
- Lys
- Substrates
- inhibitor