3-[2-(Dimethylamino)ethyl]-1H-indol-5-ol
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- CAS-Nr.
- 487-93-4
- Bezeichnung:
- 3-[2-(Dimethylamino)ethyl]-1H-indol-5-ol
- Englisch Name:
- Bufotenine
- Synonyma:
- Cohoba;DM5-HT;Mapine;Mappin;NSC 89;Mappine;bufotenin;BUFOTENINE;Bafotenine;Buffoonish
- CBNumber:
- CB0471554
- Summenformel:
- C12H16N2O
- Molgewicht:
- 204.27
- MOL-Datei:
- 487-93-4.mol
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3-[2-(Dimethylamino)ethyl]-1H-indol-5-ol Eigenschaften
- Schmelzpunkt:
- 62-64°C
- Siedepunkt:
- bp0.1 320°
- Dichte
- 1.0565 (rough estimate)
- Brechungsindex
- 1.6000 (estimate)
- Flammpunkt:
- 2℃
- storage temp.
- Refrigerator, Under Inert Atmosphere
- L?slichkeit
- Bufotenine is soluble in dilute acids and alkalis.
- pka
- 10.11±0.40(Predicted)
- EPA chemische Informationen
- 1H-Indol-5-ol, 3-[2-(dimethylamino)ethyl]- (487-93-4)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
F,Xn |
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| R-S?tze: |
11-20/21/22-36 |
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| S-S?tze: |
16-36/37 |
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| RIDADR |
1544 |
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| WGK Germany |
2 |
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| HazardClass |
6.1(b) |
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| PackingGroup |
III |
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| DEA Controlled Substances |
CSCN: 7433
CSA SCH: Schedule I
NARC: No |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H225 |
Flüssigkeit und Dampf leicht entzündbar. |
Entzündbare Flüssigkeiten |
Kategorie 2 |
Achtung |
![GHS hazard pictograms]() src="/GHS02.jpg" width="20" height="20" /> |
P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P210 |
Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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3-[2-(Dimethylamino)ethyl]-1H-indol-5-ol Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Bufotenine is an indole alkaloid obtained from the seeds and leaves of Piptadenia peregrine and P. macrocarpa. It has also been isolated from the skin glands of toads (Bufo species). The base is typically seen as white crystalline powder and the oxalate hydrate as a lavender to brown powder. The oxalate hydrate is slightly soluble in chloroform and can be separated from chloroform insoluble material for analysis.
History
Bufotenin was isolated from toad skin, and named by the Austrian chemist Handovsky at the University of Prague during World War I.The structure of bufotenine was confirmed in 1934 by Heinrich Wieland's laboratory in Munich, and the first reported synthesis of bufotenine was by Toshio Hoshino and Kenya Shimodaira in 1935.
Verwenden
Controlled substance (hallucinogen).
Bufotenine is a hallucinogenic serotonin analog found in frog and toad skins, mushrooms, plants and some mammals (especially in the brains, plasma, and urine of schizophrenics). It is a potent hallucinogen used in its natural state by several shaman sects and in some drug abuse situations in the United States and Australia. It causes schizophrenia and other psychotic symptoms.
Definition
ChEBI: Bufotenine is a tertiary amine that consists of N,N-dimethyltryptamine bearing an additional hydroxy substituent at position 5. It has a role as a hallucinogen and a coral metabolite. It is a tryptamine alkaloid and a tertiary amine. It derives from a N,N-dimethyltryptamine.
3-[2-(Dimethylamino)ethyl]-1H-indol-5-ol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-[2-(Dimethylamino)ethyl]-1H-indol-5-ol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 42)Lieferanten
487-93-4(3-[2-(Dimethylamino)ethyl]-1H-indol-5-ol)Verwandte Suche:
- BUFOTENINE
- 1H-Indol-5-ol, 3-[2-(dimethylamino)ethyl]-
- 3-(2-(dimethylamino)ethyl)-indol-5-o
- 3-(2-dimethylaminoethyl)-5-indolol
- 3-(beta-dimethylaminoethyl)-5-hydroxyindole
- 3-[2-(Dimethylamino)ethyl]-1H-indol-5-ol
- 3-[2-(Dimethylamino)ethyl]-5-indolol
- 3-[2-(Dimethylamino)ethyl]indol-5-ol
- 3-[beta-(Dimethylamino)ethyl]-5-hydroxyindole
- 5-Hydroxy-N,N-dimethyltryptamine
- bufotenin
- Cinobufotenine
- Cohoba
- Dimethylserotonin
- DM5-HT
- Indol-5-ol, 3-[2-(dimethylamino)ethyl]-
- Mapine
- Mappin
- Mappine
- N,N-Dimethyl-5-hydroxytryptamine
- N,N-Dimethylserotonin
- Bafotenine
- 3-[2-(Dimethylamino)ethyl]-5-hydroxy-1H-indole
- 3-(β-DiMethylaMinoethyl)-5-hydroxyindole
- NSC 89
- Bufotenine solution
- Buffoonish
- 487-93-4
- Amines
- Aromatics
- Heterocycles
