N-[2-(2-碘-5-甲氧基吲哚-3-基)乙基]乙酰胺
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- CAS號(hào):
- 93515-00-5
- 英文名:
- 2-IODOMELATONIN
- 英文別名:
- 2-IODOMELATONIN;Melatonin Impurity 12;Melatonin 2-Iodo Impurity;2-Iodomelatonin, 10 mM in DMSO;2Iodomelatonin,2 Iodomelatonin;N-Acetyl-2-iodo-5-methoxytryptamine;MELATONIN, 2-IODO-DERIVATIVE OF MELATON;N-[2-(2-IODO-5-METHOXYINDOL-3-YL)ETHYL]ACETAMIDE;N-Acetyl-2-iodo-5-methoxy-1H-indole-3-(ethanamine);N-[2-(2-Iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide
- 中文名:
- N-[2-(2-碘-5-甲氧基吲哚-3-基)乙基]乙酰胺
- 中文別名:
- 2-碘褪黑激素;化合物 T10073;2-碘褪黑激素,10 MM DMSO 溶液;N-[2-(2-碘-5-甲氧基吲哚-3-基)乙基]乙酰胺;N-(2-(2-碘-5-甲氧基-1H-吲哚-3-基)乙基)乙酰胺
- CBNumber:
- CB8339111
- 分子式:
- C13H15IN2O2
- 分子量:
- 358.17
- MOL File:
- 93515-00-5.mol
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N-[2-(2-碘-5-甲氧基吲哚-3-基)乙基]乙酰胺化學(xué)性質(zhì)
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沸點(diǎn):
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574.5±50.0 °C(Predicted)
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密度:
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1.630±0.06 g/cm3(Predicted)
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儲(chǔ)存條件:
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−20°C
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溶解度:
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Soluble to 100 mM in DMSO and to 100 mM in ethanol
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形態(tài):
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Powder
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酸度系數(shù)(pKa):
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15.45±0.30(Predicted)
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顏色:
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Off-white to yellow
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N-[2-(2-碘-5-甲氧基吲哚-3-基)乙基]乙酰胺性質(zhì)、用途與生產(chǎn)工藝
2-Iodomelatonin 是褪黑激素受體 1 (MT1) 的強(qiáng)效激動(dòng)劑，Ki? 為 28 pM，對(duì) MT1的選擇性是 MT2 的 5 倍以上。2-Iodomelatonin 可用于鑒定，表征和定位腦和周圍組織的褪黑激素結(jié)合位點(diǎn)。
2-iodomelatonin (0-7.5 μM; 18 hours) shares the protective properties of melatonin, it inhibits cell death of mutant htt ST14A and inhibits the increase in Rip2 expression in stressed mutant htt ST14A cells.
Cell Viability Assay
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Cell Line:
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Mutant htt ST14A cell
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Concentration:
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0 μM; 1 μM; 5 μM; 7.5 μM
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Incubation Time:
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18 hours
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Result:
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Inhibited mutant htt ST14A cell death.
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N-[2-(2-碘-5-甲氧基吲哚-3-基)乙基]乙酰胺
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS編號(hào) | 包裝 | 價(jià)格 |
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| 2025/02/08 | HY-101176 | N-[2-(2-碘-5-甲氧基吲哚-3-基)乙基]乙酰胺
2-Iodomelatonin | 93515-00-5 | 10 mM * 1 mLin DMSO | 243元 |
| 2025/02/08 | HY-101176 | N-[2-(2-碘-5-甲氧基吲哚-3-基)乙基]乙酰胺
2-Iodomelatonin | 93515-00-5 | 5mg | 308元 |
N-[2-(2-碘-5-甲氧基吲哚-3-基)乙基]乙酰胺
生產(chǎn)廠家
93515-00-5, N-[2-(2-碘-5-甲氧基吲哚-3-基)乙基]乙酰胺 相關(guān)搜索:
- Melatonin receptor
- 抑制劑
- C13H15IN2O2
- 2-碘褪黑激素,10 MM DMSO 溶液
- N-(2-(2-碘-5-甲氧基-1H-吲哚-3-基)乙基)乙酰胺
- 化合物 T10073
- N-[2-(2-碘-5-甲氧基吲哚-3-基)乙基]乙酰胺
- 2-碘褪黑激素
- 93515-00-5
- 2-Iodomelatonin, 10 mM in DMSO
- 2Iodomelatonin,2 Iodomelatonin
- Melatonin Impurity 12
- Melatonin 2-Iodo Impurity
- N-Acetyl-2-iodo-5-methoxy-1H-indole-3-(ethanamine)
- N-[2-(2-Iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide
- N-Acetyl-2-iodo-5-methoxytryptamine
- MELATONIN, 2-IODO-DERIVATIVE OF MELATON
- 2-IODOMELATONIN
- N-[2-(2-IODO-5-METHOXYINDOL-3-YL)ETHYL]ACETAMIDE
- n-(2-(2-iodo-5-methoxy-1h-indol-3-yl)ethyl)-acetamid