伊伐布雷定雜質(zhì)
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- CAS號:
- 1616710-50-9
- 英文名:
- Ivabradine IMpurity
- 英文別名:
- Y1021;I-3030;Ivabradine IMpurity;Ivabradine 2-Oxo HCl;Ivabradine Impurity T;Ivabradine Impurity 12;3-O-Desmethyl Ivabradine;Ivabradine IMpurity Y1021;Ivabradine Impurity 15 HCl;Ivabradine Impurity 37 HCl
- 中文名:
- 伊伐布雷定雜質(zhì)
- 中文別名:
- 伊伐布雷定雜質(zhì);伊伐布雷定雜質(zhì)12;伊伐布雷定氧化雜質(zhì);鹽酸伊伐布雷定雜質(zhì);伊伐布雷定雜質(zhì)對照品;鹽酸伊伐布雷定雜質(zhì)T;伊伐布雷定C1羰基雜質(zhì);伊伐布雷定雜質(zhì)15鹽酸鹽;伊伐布雷定雜質(zhì)Y1021;伊伐布雷定雜質(zhì)6 HCL
- CBNumber:
- CB72710414
- 分子式:
- C27H35ClN2O6
- 分子量:
- 519.0296
- MOL File:
- 1616710-50-9.mol
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伊伐布雷定雜質(zhì)化學(xué)性質(zhì)
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溶解度:
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DMSO (Slightly), Methanol (Slightly)
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形態(tài):
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Solid
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顏色:
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Light Yellow
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伊伐布雷定雜質(zhì)性質(zhì)、用途與生產(chǎn)工藝
在最終的伊伐布雷定制劑成品中均會有一種結(jié)構(gòu)未知且含量較大的雜質(zhì)-伊伐布雷定雜質(zhì)對照品，其產(chǎn)生無法通過制備工藝的優(yōu)化選擇而避免。不僅如此，該雜質(zhì)還具有光敏性，在隨后的制劑穩(wěn)定性實驗中發(fā)現(xiàn)，隨著實驗進程，該雜質(zhì)含量明顯增加，為制劑成品中含量最大的雜質(zhì)，其對最終出廠藥品的安全有效性有著至關(guān)重要的影響。
伊伐布雷定雜質(zhì)是一種有機物，可用作雜質(zhì)對照品。
伊伐布雷定雜質(zhì)
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
1616710-50-9, 伊伐布雷定雜質(zhì) 相關(guān)搜索:
- DCP
- 060-伊伐布雷定
- 雜質(zhì)對照品
- 對照品-雜質(zhì)對照品
- 藥物雜質(zhì)
- 雜質(zhì)對照品
- 心腦血管和血液
- 伊伐布雷定雜質(zhì)10 HCL
- 伊伐布雷定雜質(zhì)37 鹽酸鹽
- 伊伐布雷定雜質(zhì)33 鹽酸鹽
- (S)-3-(3-(((3,4-二甲氧基雙環(huán)[4.2.0]八-1(6),2,4-三烯-7-基)甲基)(甲基)氨基)丙基)-7,8-二甲氧基-4,5-二氫-1H-苯并[D]氮雜環(huán)-1,2(3H)-二酮鹽酸鹽 (伊伐布雷定雜質(zhì))
- 鹽酸伊伐布雷定雜質(zhì)T
- 伊伐布雷定雜質(zhì)15對照品
- 伊伐布雷定雜質(zhì)6 HCL
- 伊伐布雷定C1羰基雜質(zhì)
- 伊伐布雷定氧化雜質(zhì)
- 伊伐布雷定雜質(zhì)15鹽酸鹽
- 伊伐布雷定雜質(zhì)Y1021
- 3-(3-{[((7S)-3,4-二甲氧基雙環(huán)[4.2.0]辛-1,3,5-三烯-7-基)甲基]甲基氨基}丙基)-1,3,4,5-四氫-7,8-二甲氧基-2H-3-苯并氮雜卓-1,2-二酮草酸鹽
- 伊伐布雷定雜質(zhì)12
- 3-(3-{[((7S)-3,4-二甲氧基雙環(huán)[4.2.0]辛-1,3,5-三烯-7-基)甲基]甲基氨基}丙基)-1,3,4,5-四氫-7,8-二甲氧基-2H-3-苯并氮雜卓-1,2-二酮
- 伊伐布雷定雜質(zhì)對照品
- 伊伐布雷定雜質(zhì)15 HCL
- 伊伐布雷定雜質(zhì)
- 鹽酸伊伐布雷定雜質(zhì)
- 1616710-50-9
- Ivabradine Impurity 10 HCl
- Ivabradine Impurity 37 HCl
- 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-4,5-dihydro-7,8-dimethoxy-1H-3-benzazepine-1,2(3H)-dione
- (S)-3-(3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepine-1,2(3H)-dione hydrochloride (Ivabradine Impurity)
- 3-(3-{[((7S)-3,4-dimethoxybicyclo[4.2.0]oct-1,3,5-trien-7-yl)methyl]methylamino}propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzoazazepine-1,2-dione
- (S)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepine-1,2(3H)-dione hydrochloride
- Ivabradine 2-Oxo HCl
- Y1021
- I-3030
- Ivabradine Impurity T
- Ivabradine Impurity 15 HCl
- Ivabradine IMpurity Y1021
- 3-(3-((2-(3,4-dimethoxyphenyl)propyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one hydrochloride
- (R)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one hydrochloride
- (S)-2-(2-(2-((3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)amino)ethyl)-4,5-dimethoxyphenyl)acetic acid hydrochloride
- Ivabradine hydrochloride impurity
- Hydrochloride Ivabradine IMP
- Ivabradine Impurity 12
- 3-O-Desmethyl Ivabradine
- Ivabradine IMpurity