APILIMOD MESYLATE
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- CAS號(hào):
- 870087-36-8
- 英文名:
- ApiliMod (Mesylate)
- 英文別名:
- STA5326 mesylate;Apilimodmesilate;STA-5326 mesylate;STA 5326 mesylate;Apilimod dimesylate;ApiliMod (Mesylate);Apilimodmesylate, >98%;Apilimod (STA-5326) mesylate;STA 5326 MESYLATE; STA5326 MESYLATE; STA-5326 MESYLATE;Apilimod,inhibit,Interleukin Related,STA-5326,Fab1,STA5326,STA 5326,Apilimod mesylate,Inhibitor,PIKfyve
- 中文名:
- APILIMOD MESYLATE
- 中文別名:
- 阿匹莫德甲磺酸鹽;阿吡莫德甲磺酸鹽;阿匹莫德二甲磺酸酯;阿吡莫德二甲磺酸鹽;APILIMOD甲磺酸鹽;阿吡莫德甲磺酸鹽, >98%;4-(6-(2-(3-甲基亞芐基)肼基)-2-(2-(吡啶-2-基)乙氧基)嘧啶-4-基)嗎啉二甲基磺酸鹽
- CBNumber:
- CB72685921
- 分子式:
- C24H30N6O5S
- 分子量:
- 514.6
- MOL File:
- 870087-36-8.mol
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APILIMOD MESYLATE化學(xué)性質(zhì)
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儲(chǔ)存條件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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形態(tài):
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Powder
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顏色:
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White to off-white
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APILIMOD MESYLATE性質(zhì)、用途與生產(chǎn)工藝
Apilimod mesylate (STA-5326 mesylate) 是一種有效的細(xì)胞因子 interleukin-12 (IL-12) 和 interleukin-23 (IL-23) 的口服抑制劑，具有治療某些自身免疫和炎性疾病的潛力。Apilimod mesylate (STA-5326 mesylate) 可抑制IL-12，在IFN-γ/SAC刺激的人PBMC細(xì)胞、人單核細(xì)胞和小鼠PBMC細(xì)胞中，對(duì)應(yīng)的IC50值分別為1 nM、1 nM和2 nM。Apilimod mesylate (STA-5326 mesylate) 也是一種具有細(xì)胞通透性的小分子化合物，抑制PIKfyve，IC50為14 nM。
| Target | Value |
IL-12
(in IFN-γ/SAC-stimulated human PBMCs)
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1 nM
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IL-12
(in human monocytes)
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1 nM
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IL-12
(in mouse PBMCs)
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2 nM
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PIKfyve
(Cell-free assay)
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14 nM
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APILIMOD MESYLATE
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS編號(hào) | 包裝 | 價(jià)格 |
|---|
| 2024/11/11 | XW87008736803 | 阿吡莫德甲磺酸鹽 | 870087-36-8 | 5MG | 138元 |
| 2024/11/11 | XW87008736801 | 阿吡莫德甲磺酸鹽 | 870087-36-8 | 100MG | 810元 |
APILIMOD MESYLATE
生產(chǎn)廠家
870087-36-8, APILIMOD MESYLATE 相關(guān)搜索:
- 抑制劑
- 藥靶配體
- C23H26N6O22CH4O3S
- 阿匹莫德二甲磺酸酯
- 阿吡莫德二甲磺酸鹽
- 4-(6-(2-(3-甲基亞芐基)肼基)-2-(2-(吡啶-2-基)乙氧基)嘧啶-4-基)嗎啉二甲基磺酸鹽
- APILIMOD甲磺酸鹽
- 阿匹莫德甲磺酸鹽
- 阿吡莫德甲磺酸鹽, >98%
- 阿吡莫德甲磺酸鹽
- 870087-36-8
- Benzaldehyde, 3-methyl-,[6-(4-morpholinyl)-2-[2-(2-pyridinyl)ethoxy]-4-pyrimidinyl]hydrazone,dimethanesulfonate
- Apilimod (STA-5326) mesylate
- Apilimod,inhibit,Interleukin Related,STA-5326,Fab1,STA5326,STA 5326,Apilimod mesylate,Inhibitor,PIKfyve
- 4-(6-(2-(3-Methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine dimethanesulfonate
- (E)-4-(6-(2-(3-Methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine dimethanesulfonate
- Apilimodmesilate
- Apilimodmesylate, >98%
- STA-5326 mesylate
- STA5326 mesylate
- STA 5326 MESYLATE; STA5326 MESYLATE; STA-5326 MESYLATE
- STA 5326 mesylate
- Apilimod dimesylate
- (E)-4-(6-(2-(3-methylbenzylidene)hydrazinyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine methanesulfonate
- ApiliMod (Mesylate)