ChemicalBook CAS DataBase List N-(CYANOMETHYL)ACETAMIDE

N-(CYANOMETHYL)ACETAMIDE synthesis

7synthesis methods

Product Name:N-(CYANOMETHYL)ACETAMIDE
CAS Number:4814-80-6
Molecular formula:C4H6N2O
Molecular Weight:98.1

6011-14-9 Synthesis

6011-14-9
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$5.00/10g

10387-40-3 Synthesis

10387-40-3
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$10.00/1g

4814-80-6
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$58.00/100mg

Yield:4814-80-6 99 %Spectr.

Reaction Conditions:

with sodium hydroxide;potassium hexacyanoferrate(III) in water at 20; pH=9; for 0.333333 h;

Steps:

Acetylation of α-aminonitriles with thioacetate.

General procedure: α-Aminonitrile hydrochloride (AA-CN*HCl; 50 mM) and potassium thioacetate (AcSK; 150 mM) were dissolved in H₂O (2 ml) and the solution was adjusted topH 9.0 with NaOH. Potassium hexacyanoferrate(III) (K3[Fe(CN)6]; 450 mM) was added, and the solution was stirred at room temperature for 20 min. The solution was adjusted to pH 9.0 and centrifuged, and NMR spectra of the supernatant were acquired. Yields are reported in Table 1 and characterization data in Supplementary Information.

References:

Canavelli, Pierre;Islam, Saidul;Powner, Matthew W. [Nature,2019,vol. 571,# 7766,p. 546 - 549]

6011-14-9 Synthesis

6011-14-9
368 suppliers
$5.00/10g