奧米沙班
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- CAS號(hào):
- 193153-04-7
- 英文名:
- Methyl (2R,3R)-2-[3-amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate
- 英文別名:
- FXV 673;Preluent;FXV673/FXV-673;OtaMixaban (FXV 673);FXV 673; FXV673; FXV-673;Methyl (2R,3R)-2-[3-amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate;Methyl (2R,3R)-2-{3-[aMino(iMino)Methyl]benzyl}-3-{[4-(1-oxidopyridin-4-yl)benzoyl]aMino}butanoate;methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(1-oxidopyridin-1-ium-4-yl)benzoyl]amino]butanoate;(αR)-3-(AMinoiMinoMethyl)-α-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]aMino]ethyl]benzenepropanoic Acid Methyl Ester;[R-(R*,R*)]-3-(AMinoiMinoMethyl)-α-[1-[[4-(1-oxido-4-pyridinyl)benzoyl]aMino]ethyl]benzenepropanoic Acid Methyl Ester
- 中文名:
- 奧米沙班
- 中文別名:
- 奧美沙班;化合物 T16410;(2R,3R)-2-(3-甲脒基-芐基)-3-[4-(1-氧基-吡啶-4-基)苯甲酰]氨基}-丁酸甲酯;甲基(2R,3R)-2-{3-[氨基(亞胺基)甲基]芐基}-3-{[4-(1-氧化吡啶-4-YL)苯甲酰]氨基}戊酯
- CBNumber:
- CB62510035
- 分子式:
- C25H26N4O4
- 分子量:
- 446.5
- MOL File:
- 193153-04-7.mol
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奧米沙班化學(xué)性質(zhì)
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密度:
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1.25
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儲(chǔ)存條件:
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Store at -20°C
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溶解度:
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≥22.35 mg/mL in DMSO; insoluble in H2O; ≥55 mg/mL in EtOH with gentle warming
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形態(tài):
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Powder
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酸度系數(shù)(pKa):
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13.38±0.46(Predicted)
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顏色:
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Light yellow to yellow
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奧米沙班性質(zhì)、用途與生產(chǎn)工藝
Otamixaban（FXV673）是高效的fXa選擇性可逆型抑制劑，Ki為0.5nM，能抑制游離型或凝血酶原酶結(jié)合型fXa。
奧米沙班
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
193153-04-7, 奧米沙班 相關(guān)搜索:
- Heterocycles
- Aromatics
- Amines
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Inhibitors
- 雜質(zhì)對(duì)照品
- 抑制劑
- 信號(hào)轉(zhuǎn)導(dǎo)通路激酶抑制劑
- 奧美沙班
- 化合物 T16410
- (2R,3R)-2-(3-甲脒基-芐基)-3-[4-(1-氧基-吡啶-4-基)苯甲酰]氨基}-丁酸甲酯
- 甲基(2R,3R)-2-{3-[氨基(亞胺基)甲基]芐基}-3-{[4-(1-氧化吡啶-4-YL)苯甲酰]氨基}戊酯
- 193153-04-7
- Benzenepropanoic acid, 3-(aminoiminomethyl)-α-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]ethyl]-, methyl ester, (αR)-
- methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(1-oxidopyridin-1-ium-4-yl)benzoyl]amino]butanoate
- FXV 673; FXV673; FXV-673
- Preluent
- Methyl (2R,3R)-2-{3-[aMino(iMino)Methyl]benzyl}-3-{[4-(1-oxidopyridin-4-yl)benzoyl]aMino}butanoate
- FXV673/FXV-673
- OtaMixaban (FXV 673)
- FXV 673
- [R-(R*,R*)]-3-(AMinoiMinoMethyl)-α-[1-[[4-(1-oxido-4-pyridinyl)benzoyl]aMino]ethyl]benzenepropanoic Acid Methyl Ester
- (αR)-3-(AMinoiMinoMethyl)-α-[(1R)-1-[[4-(1-oxido-4-pyridinyl)benzoyl]aMino]ethyl]benzenepropanoic Acid Methyl Ester
- Methyl (2R,3R)-2-[3-amidinobenzyl]-3-[[4-(1-oxido-4-pyridinyl)benzoyl]amino]butanoate