BIBF0775
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- CAS號(hào):
- 334951-90-5
- 英文名:
- BIBF0775
- 英文別名:
- BIBF0775;BIBF 0775,BIBF-0775,inhibit,Transforming growth factor beta receptors,BIBF0775,TGF-β Receptor,Inhibitor;(3Z)-N-ethyl-N-methyl-2-oxo-3-[phenyl-[4-(piperidin-1-ylmethyl)anilino]methylidene]-1H-indole-6-carboxamide;(Z)-N-Ethyl-N-methyl-2-oxo-3-(phenyl((4-(piperidin-1-ylmethyl)phenyl)amino)methylene)indoline-6-carboxamide;1H-Indole-6-carboxamide, N-ethyl-2,3-dihydro-N-methyl-2-oxo-3-[phenyl[[4-(1-piperidinylmethyl)phenyl]amino]methylene]-, (3Z)-
- 中文名:
- BIBF0775
- 中文別名:
- 化合物BIBF0775;(Z)-N-乙基-N-甲基-2-氧代-3-(苯基((4-(哌啶-1-基甲基)苯基)氨基)亞甲基)二氫吲哚-6-甲酰胺
- CBNumber:
- CB52667945
- 分子式:
- C31H34N4O2
- 分子量:
- 494.63
- MOL File:
- 334951-90-5.mol
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BIBF0775化學(xué)性質(zhì)
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沸點(diǎn):
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705.9±60.0 °C(Predicted)
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密度:
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1.223±0.06 g/cm3(Predicted)
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儲(chǔ)存條件:
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Sealed in dry,Room Temperature
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溶解度:
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DMSO:38.25(Max Conc. mg/mL);77.33(Max Conc. mM)
Ethanol:2.0(Max Conc. mg/mL);4.04(Max Conc. mM)-
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酸度系數(shù)(pKa):
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11.33±0.20(Predicted)
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形態(tài):
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Solid
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顏色:
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Light yellow to yellow
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BIBF0775性質(zhì)、用途與生產(chǎn)工藝
BIBF-0775是transforming growth factor β Receptor I (TGFβRI,Alk5)的選擇性抑制劑，IC50為34 nM。
| Target | Value |
ALK5
(Cell-free assay)
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34 nM
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BIBF0775
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS編號(hào) | 包裝 | 價(jià)格 |
|---|
| 2024/11/08 | HY-13783 | BIBF0775
BIBF0775 | 334951-90-5 | 5mg | 1800元 |
| 2024/11/08 | HY-13783 | BIBF0775
BIBF0775 | 334951-90-5 | 10mM * 1mLin DMSO | 1980元 |
334951-90-5, BIBF0775 相關(guān)搜索:
- 抑制劑
- 藥靶配體
- 對(duì)照品
- (Z)-N-乙基-N-甲基-2-氧代-3-(苯基((4-(哌啶-1-基甲基)苯基)氨基)亞甲基)二氫吲哚-6-甲酰胺
- 化合物BIBF0775
- 334951-90-5
- BIBF 0775,BIBF-0775,inhibit,Transforming growth factor beta receptors,BIBF0775,TGF-β Receptor,Inhibitor
- (Z)-N-Ethyl-N-methyl-2-oxo-3-(phenyl((4-(piperidin-1-ylmethyl)phenyl)amino)methylene)indoline-6-carboxamide
- 1H-Indole-6-carboxamide, N-ethyl-2,3-dihydro-N-methyl-2-oxo-3-[phenyl[[4-(1-piperidinylmethyl)phenyl]amino]methylene]-, (3Z)-
- (3Z)-N-ethyl-N-methyl-2-oxo-3-[phenyl-[4-(piperidin-1-ylmethyl)anilino]methylidene]-1H-indole-6-carboxamide
- BIBF0775