hDHODH-IN-1
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- CAS號(hào):
- 1173715-42-8
- 英文名:
- hDHODH-IN-1
- 英文別名:
- hDHODH-IN-1;2-Butenamide, N-[1,1'-biphenyl]-4-yl-2-cyano-3-hydroxy-;N-([1,1'-Biphenyl]-4-yl)-2-cyano-3-hydroxybut-2-enamide;N-([1,1'-Biphenyl]-4-yl)-2-cyano-3-hydroxybut-2-enamide;hDHODH,proliferating-cell,Inhibitor,DNA/RNA Synthesis,dihydroorotate,anti-inflammatory,inhibit,hDHODH IN 1,dehydrogenase,LDH,human,Lactate Dehydrogenase,hDHODHIN1
- 中文名:
- hDHODH-IN-1
- 中文別名:
- 化合物 T11546;化合物HDHODH-IN-1;N-([1,1'-聯(lián)苯]-4-基)-2-氰基-3-羥基丁-2-烯酰胺;N-([1,1'-聯(lián)苯]-4-基)-2-氰基-3-羥基丁-2-烯酰胺
- CBNumber:
- CB15855428
- 分子式:
- C17H14N2O2
- 分子量:
- 278.31
- MOL File:
- 1173715-42-8.mol
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hDHODH-IN-1化學(xué)性質(zhì)
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熔點(diǎn):
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270-275 °C (decomp)
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沸點(diǎn):
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514.6±50.0 °C(Predicted)
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密度:
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1.256±0.06 g/cm3(Predicted)
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儲(chǔ)存條件:
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Store at -20°C
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溶解度:
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DMSO: 250 mg/mL (898.28 mM)
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酸度系數(shù)(pKa):
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5.20±0.50(Predicted)
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形態(tài):
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Solid
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顏色:
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Off-white to light yellow
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hDHODH-IN-1性質(zhì)、用途與生產(chǎn)工藝
hDHODH-IN-1 是一種人二氫乳清酸脫氫酶 (hDHODH) 抑制劑， 具有抗炎作用。
Human dihydroorotate dehydrogenase (hDHODH) is a class-2 dihydroorotate dehydrogenase. Because DHODH is required to ensure proliferating-cell viability, inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers, multiple sclerosis, and autoimmune and inflammatory diseases.
hDHODH-IN-1
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS編號(hào) | 包裝 | 價(jià)格 |
|---|
| 2024/11/08 | HY-135658 | hDHODH-IN-1
hDHODH-IN-1 | 1173715-42-8 | 5 mg | 2000元 |
| 2024/11/08 | HY-135658 | hDHODH-IN-1
hDHODH-IN-1 | 1173715-42-8 | 10mM * 1mLin DMSO | 2200元 |
1173715-42-8, hDHODH-IN-1 相關(guān)搜索:
- 抑制劑
- 藥靶配體
- N-([1,1'-聯(lián)苯]-4-基)-2-氰基-3-羥基丁-2-烯酰胺
- N-([1,1'-聯(lián)苯]-4-基)-2-氰基-3-羥基丁-2-烯酰胺
- 化合物HDHODH-IN-1
- 化合物 T11546
- 1173715-42-8
- N-([1,1'-Biphenyl]-4-yl)-2-cyano-3-hydroxybut-2-enamide
- N-([1,1'-Biphenyl]-4-yl)-2-cyano-3-hydroxybut-2-enamide
- hDHODH,proliferating-cell,Inhibitor,DNA/RNA Synthesis,dihydroorotate,anti-inflammatory,inhibit,hDHODH IN 1,dehydrogenase,LDH,human,Lactate Dehydrogenase,hDHODHIN1
- 2-Butenamide, N-[1,1'-biphenyl]-4-yl-2-cyano-3-hydroxy-
- hDHODH-IN-1