二氟比魯卡胺
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- CAS號(hào):
- 90357-05-4
- 英文名:
- Desfluoro Bicalutamide
- 英文別名:
- Bicalutamide-EP-Imp-A;Desfluoro Bicalutamide;Bicalutamide impurity B;Bicalutamide EP Impurity A;Bicalutamide Impurity 3(EP Impurity A);Bicalutamide EP Impurity A(desflurbicalutamide);Bicalutamide Impurity 3(Bicalutamide EP Impurity A);Bicalutamide EP Impurity A (Desfluoro Bicalutamide);3-(benzenesulfonyl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide;Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylsulfonyl)-
- 中文名:
- 二氟比魯卡胺
- 中文別名:
- 脫氟比卡魯胺;去氟比卡魯胺;二氟比魯卡胺;去氟代比卡魯胺;比卡魯胺EP雜質(zhì)A;比卡魯胺雜質(zhì)A(EP);比卡魯胺EP雜質(zhì)A(去氟比卡魯胺);比卡魯胺EP雜質(zhì)A(脫氟比卡魯胺);比卡魯胺雜質(zhì)3(比卡魯胺EP雜質(zhì)A);N-[4-氰基-3-(三氟甲基)苯基]-2-羥基-2-甲基-3-(苯磺?；?丙酰胺
- CBNumber:
- CB02487014
- 分子式:
- C18H15F3N2O4S
- 分子量:
- 412.38
- MOL File:
- 90357-05-4.mol
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二氟比魯卡胺化學(xué)性質(zhì)
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熔點(diǎn):
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175-178 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
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沸點(diǎn):
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656.1±55.0 °C(Predicted)
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密度:
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1.48±0.1 g/cm3(Predicted)
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儲(chǔ)存條件:
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Refrigerator
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溶解度:
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Chloroform (Sparingly, Sonicated), Methanol (Sparingly)
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形態(tài):
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Solid
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酸度系數(shù)(pKa):
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11.22±0.29(Predicted)
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顏色:
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White to Off-White
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CAS 數(shù)據(jù)庫(kù):
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90357-05-4
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二氟比魯卡胺性質(zhì)、用途與生產(chǎn)工藝
二氟比魯卡胺是比卡魯胺EP雜質(zhì)A。比卡魯胺是由英國(guó)Astra Zeneca公司研發(fā)成功，1995年首次在英國(guó)上市。本藥用于治療前列腺癌，它是應(yīng)用最為廣泛的抗雄性激素藥物。
二氟比魯卡胺是比卡魯胺EP雜質(zhì)A。比卡魯胺(Bicalutamide)作為非甾體抗雄性激素化合物，能反饋抑制垂體前葉分泌促性腺，可減少雄性激素的產(chǎn)生卻幾乎無(wú)雄性激素活性。
二氟比魯卡胺
上下游產(chǎn)品信息
上游原料
下游產(chǎn)品
90357-05-4, 二氟比魯卡胺 相關(guān)搜索:
- Sulfur & Selenium Compounds
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Impurities
- Aromatics
- 雜質(zhì)對(duì)照品
- 標(biāo)準(zhǔn)品
- 比卡魯胺雜質(zhì)3(比卡魯胺EP雜質(zhì)A)
- 比卡魯胺EP雜質(zhì)A(去氟比卡魯胺)
- 比卡魯胺EP雜質(zhì)A(脫氟比卡魯胺)
- 去氟比卡魯胺
- 比卡魯胺雜質(zhì)A(EP)
- 比卡魯胺EP雜質(zhì)A
- N-[4-氰基-3-(三氟甲基)苯基]-2-羥基-2-甲基-3-(苯磺?；?丙酰胺
- 二氟比魯卡胺
- 去氟代比卡魯胺
- 脫氟比卡魯胺
- 90357-05-4
- Bicalutamide EP Impurity A(desflurbicalutamide)
- Bicalutamide Impurity AQ: What is
Bicalutamide Impurity A Q: What is the CAS Number of
Bicalutamide Impurity A Q: What is the storage condition of
Bicalutamide Impurity A Q: What are the applications of
Bicalutamide Impurity A
- Bicalutamide Impurity 3(Bicalutamide EP Impurity A)
- Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylsulfonyl)-
- Bicalutamide Impurity 3(EP Impurity A)
- Bicalutamide impurity B
- 3-(benzenesulfonyl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
- Bicalutamide EP Impurity A (Desfluoro Bicalutamide)
- Bicalutamide-EP-Imp-A
- (+/-)-N-[4-Cyano-3-(trifluoroMethyl)phenyl]-2-hydroxy-2-Methyl-3-(phenylsulfonyl)propanaMide
- Bicalutamide EP Impurity A
- Desfluoro Bicalutamide