98603-84-0
![98603-84-0 結(jié)構(gòu)式](/CAS/GIF/98603-84-0.gif)
基本信息
SSEA 1
3′-SLeX
Lewis Sugars
SIALYL LEWIS X
Sialyl Lex tri
3'-SIALYL LEWIS
3'-SIALYL-LEWISX
SLEX, SODIUM SALT
Sialyl Lewisx (S Lex)
物理化學(xué)性質(zhì)
報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
2025/02/08 | HY-W020790 | 唾液酸化酶X Sialyl-Lewis X | 98603-84-0 | 1mg | 3360元 |
2023/03/20 | HY-W020790 | 唾液酸化酶X Sialyl-Lewis X | 98603-84-0 | 5mg | 16500元 |
常見(jiàn)問(wèn)題列表
Sialyl-Lewis X is a high-affinity ligand of CD62, Antibodies [mAb CSLEX (IgM; anti-sLeX)] to sLeX inhibit CD62-mediated binding of HL-60 cells to activated platelets.Liposomes containing glycolipids with the sLeX structure prevents adhesion of HL-60 cells and human neutrophils. HL-60 cell adhesion is partially inhibited (50%) by liposomes containing Lex at 5 μg/ml. However, sLeX liposomes give maximal inhibition at only 1 ug/ml. sLeX liposomes inhibits adhesion with a 10-fold higher affinity than Lex liposomes.CD62 binding of neutrophils to activated platelets is inhibited a soluble human milk oligosaccharide that contains the LeX structure. the sLeX sugar is a 30-fold more potent inhibitor than the nonsialylated Lex sugar, which requires 2 μg/ml and 54 μg/ml to achieve 50% inhibition of neutrophil adhesion, respectively.