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98320-39-9

中文名稱 IX 207-887
英文名稱 (Z)-10-METHOXY-4H-BENZO[4,5]CYCLOHEPTA[1,2-B]THIOPHENE-4-YLIDENE ACETIC ACID
CAS 98320-39-9
分子式 C16H12O3S
分子量 284.33
MOL 文件 98320-39-9.mol
98320-39-9 結(jié)構(gòu)式 98320-39-9 結(jié)構(gòu)式

基本信息

中文別名
化合物 T11697
英文別名
IX 207-887
[10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene]acetic acid
Acetic acid, 2-(10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-
(Z)-10-METHOXY-4H-BENZO[4,5]CYCLOHEPTA[1,2-B]THIOPHENE-4-YLIDENE ACETIC ACID

物理化學(xué)性質(zhì)

沸點475.0±45.0 °C(Predicted)
密度1.37±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)3.81±0.41(Predicted)
形態(tài)Solid
顏色Light yellow to yellow
IX 207-887價格(試劑級)
報價日期產(chǎn)品編號產(chǎn)品名稱CAS號包裝價格
2025/02/08HY-106087IX 207-88798320-39-95 mg1300元
2025/02/08HY-106087IX 207-88798320-39-910 mM * 1 mLin DMSO1430元
2025/02/08HY-106087IX 207-88798320-39-910 mg2100元

常見問題列表

生物活性
IX 207-887 是一種新型抗關(guān)節(jié)炎藥物, 也能抑制白細胞介素-1 (IL-1) 的釋放。
靶點

IL-1

體外研究

IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed.

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